SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2r7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 2r7h PUTATIVE D-ALANINE
N-ACETYLTRANSFERASE
OF GNAT FAMILY
(Desulfovibrio
alaskensis) 		4 / 7 CYH A  83
TYR A  84
TYR A  67
HIS A  58
 None
 1.22A 1yvmA-2r7hA:
undetectable		 1yvmA-2r7hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 2r7h PUTATIVE D-ALANINE
N-ACETYLTRANSFERASE
OF GNAT FAMILY
(Desulfovibrio
alaskensis) 		5 / 12 GLY A  80
GLY A 111
ALA A 113
VAL A  33
MET A  78
 None
 1.01A 2nyuA-2r7hA:
undetectable		 2nyuA-2r7hA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2r7h PUTATIVE D-ALANINE
N-ACETYLTRANSFERASE
OF GNAT FAMILY
(Desulfovibrio
alaskensis) 		4 / 8 LEU A  96
LEU A 130
VAL A 118
GLY A  85
 None
 0.73A 3dcjB-2r7hA:
undetectable		 3dcjB-2r7hA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 2r7h PUTATIVE D-ALANINE
N-ACETYLTRANSFERASE
OF GNAT FAMILY
(Desulfovibrio
alaskensis) 		4 / 7 ARG A  23
ALA A 116
ILE A  99
LEU A  96
 None
 0.79A 5te8C-2r7hA:
undetectable		 5te8C-2r7hA:
15.10