SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ra8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		4 / 8 PHE A 138
LEU A 144
GLY A 143
PHE A 141
 None
 0.84A 1rtsA-2ra8A:
undetectable		 1rtsA-2ra8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 9 LEU A 273
ILE A 286
PHE A 272
LEU A 309
ILE A 306
 None
 1.28A 2f78B-2ra8A:
undetectable		 2f78B-2ra8A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 12 LEU A 177
ASN A 176
LEU A 195
MET A 171
VAL A 167
 None
 1.43A 2q7iA-2ra8A:
undetectable		 2q7iA-2ra8A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 12 LEU A 177
ASN A 176
LEU A 195
MET A 171
VAL A 167
 None
 1.39A 2q7kA-2ra8A:
undetectable		 2q7kA-2ra8A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 12 LEU A 177
ASN A 176
LEU A 195
MET A 171
VAL A 167
 None
 1.42A 2q7lA-2ra8A:
undetectable		 2q7lA-2ra8A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		3 / 3 GLY A 188
ASP A 212
SER A 216
 None
 0.58A 2qhfA-2ra8A:
undetectable		 2qhfA-2ra8A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 12 LEU A 177
ASN A 176
LEU A 195
MET A 171
VAL A 167
 None
 1.44A 2yloA-2ra8A:
undetectable		 2yloA-2ra8A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		4 / 6 GLY A 229
VAL A 228
ASP A 261
THR A 353
 None
 1.08A 3vqrA-2ra8A:
undetectable		 3vqrA-2ra8A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		4 / 5 GLY A 229
VAL A 228
ASP A 261
THR A 353
 None
 1.08A 3vqrB-2ra8A:
undetectable		 3vqrB-2ra8A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		4 / 8 PHE A 141
HIS A 140
GLU A 136
ILE A 131
 None
 1.28A 4cx7A-2ra8A:
undetectable
4cx7B-2ra8A:
undetectable		 4cx7A-2ra8A:
21.78
4cx7B-2ra8A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 11 VAL A   6
LEU A  32
GLU A  70
ALA A  73
THR A  68
 None
 1.11A 4e0fA-2ra8A:
undetectable		 4e0fA-2ra8A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 10 SER A 197
GLN A 161
LEU A 185
LEU A 164
LEU A 177
 None
 1.10A 4yiaA-2ra8A:
undetectable		 4yiaA-2ra8A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		4 / 7 TYR A  83
LYS A  81
SER A 108
LEU A 106
 None
 0.96A 5bphB-2ra8A:
undetectable		 5bphB-2ra8A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		4 / 7 PHE A 138
LEU A 144
GLY A 143
PHE A 141
 None
 0.72A 5h3aB-2ra8A:
undetectable		 5h3aB-2ra8A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 12 GLY A 289
ALA A 288
GLY A 258
ILE A 259
SER A 202
 None
 0.74A 5t2zB-2ra8A:
undetectable		 5t2zB-2ra8A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		5 / 12 MET A 171
ALA A 128
LEU A 144
ILE A 112
ASP A 148
 None
 1.24A 5vlmG-2ra8A:
undetectable		 5vlmG-2ra8A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		4 / 8 PHE A 138
LEU A 144
GLY A 143
PHE A 141
 None
 0.80A 5x5qD-2ra8A:
undetectable		 5x5qD-2ra8A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 2ra8 UNCHARACTERIZED
PROTEIN Q64V53_BACFR
(Bacteroides
fragilis) 		4 / 8 PHE A 138
LEU A 144
GLY A 143
PHE A 141
 None
 0.79A 5x5qF-2ra8A:
undetectable		 5x5qF-2ra8A:
22.19