SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ra9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 2ra9 UNCHARACTERIZED
PROTEIN DUF1285
(Shewanella
baltica) 		4 / 8 PHE A 145
GLY A 138
LEU A  87
PHE A  91
 None
EDO  A 161 (-3.6A)
None
EDO  A 160 ( 3.9A)
 0.82A 1gsfC-2ra9A:
undetectable		 1gsfC-2ra9A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 2ra9 UNCHARACTERIZED
PROTEIN DUF1285
(Shewanella
baltica) 		3 / 3 LEU A 127
PRO A 128
ARG A  93
 None
 0.59A 2qd5A-2ra9A:
undetectable		 2qd5A-2ra9A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2ra9 UNCHARACTERIZED
PROTEIN DUF1285
(Shewanella
baltica) 		5 / 12 PHE A  57
ALA A  54
THR A  43
GLY A  40
LEU A 133
 None
 1.44A 3aobC-2ra9A:
undetectable		 3aobC-2ra9A:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 2ra9 UNCHARACTERIZED
PROTEIN DUF1285
(Shewanella
baltica) 		3 / 3 VAL A  89
GLY A 138
LYS A 136
 None
EDO  A 161 (-3.6A)
EDO  A 161 ( 4.2A)
 0.77A 4k50A-2ra9A:
undetectable		 4k50A-2ra9A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 2ra9 UNCHARACTERIZED
PROTEIN DUF1285
(Shewanella
baltica) 		3 / 3 VAL A  89
GLY A 138
LYS A 136
 None
EDO  A 161 (-3.6A)
EDO  A 161 ( 4.2A)
 0.75A 4k50E-2ra9A:
undetectable		 4k50E-2ra9A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 2ra9 UNCHARACTERIZED
PROTEIN DUF1285
(Shewanella
baltica) 		3 / 3 VAL A  89
GLY A 138
LYS A 136
 None
EDO  A 161 (-3.6A)
EDO  A 161 ( 4.2A)
 0.75A 4k50I-2ra9A:
undetectable		 4k50I-2ra9A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ra9 UNCHARACTERIZED
PROTEIN DUF1285
(Shewanella
baltica) 		3 / 3 LEU A 127
PRO A 128
ARG A  93
 None
 0.64A 4klrB-2ra9A:
undetectable		 4klrB-2ra9A:
18.02