SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rbb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 6 ASN A  83
HIS A  85
ALA A  87
TYR A  88
 None
 1.13A 1l5qA-2rbbA:
undetectable		 1l5qA-2rbbA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 6 ASN A  83
HIS A  85
ALA A  87
TYR A  88
 None
 1.12A 1l5qB-2rbbA:
undetectable		 1l5qB-2rbbA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		3 / 3 LEU A  73
ARG A  71
ILE A  80
 None
 0.59A 2xn5B-2rbbA:
undetectable		 2xn5B-2rbbA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 6 ASN A  83
HIS A  85
ALA A  87
TYR A  88
 None
 1.13A 3dd1A-2rbbA:
undetectable		 3dd1A-2rbbA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 6 ASN A  83
HIS A  85
ALA A  87
TYR A  88
 None
 1.14A 3ddsA-2rbbA:
undetectable		 3ddsA-2rbbA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 6 ASN A  83
HIS A  85
ALA A  87
TYR A  88
 None
 1.13A 3ddsB-2rbbA:
undetectable		 3ddsB-2rbbA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 6 ASN A  83
HIS A  85
ALA A  87
TYR A  88
 None
 1.14A 3ddwA-2rbbA:
undetectable		 3ddwA-2rbbA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 6 ASN A  83
HIS A  85
ALA A  87
TYR A  88
 None
 1.14A 3ddwB-2rbbA:
undetectable		 3ddwB-2rbbA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 7 ILE A  41
PHE A  57
TYR A  53
GLY A  72
 None
 1.04A 3em0B-2rbbA:
undetectable		 3em0B-2rbbA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Paraburkholderia
phytofirmans) 		4 / 6 LEU A 105
LEU A 146
VAL A 145
PHE A 108
 None
 1.22A 4uswA-2rbbA:
undetectable		 4uswA-2rbbA:
15.16