SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rbd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRK_A_TFPA204_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2rbd	BH2358 PROTEIN (Bacillus halodurans)	5 / 9	PHE A 136 LEU A 69 PHE A 133 MET A 132 LEU A 25	None	1.36A	1wrkA-2rbdA: undetectable 1wrkB-2rbdA: undetectable	1wrkA-2rbdA: 16.77 1wrkB-2rbdA: 16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1507_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	2rbd	BH2358 PROTEIN (Bacillus halodurans)	3 / 3	GLN A 123 HIS A 14 ARG A 126	None	0.95A	1zlqA-2rbdA: undetectable	1zlqA-2rbdA: 14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7P_A_ACRA1431_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	2rbd	BH2358 PROTEIN (Bacillus halodurans)	4 / 7	ASN A 153 ASP A 46 TRP A 156 GLY A 43	None	1.14A	5x7pA-2rbdA: undetectable	5x7pA-2rbdA: 8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A93_B_8NUB3001_1 (5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562)	2rbd	BH2358 PROTEIN (Bacillus halodurans)	4 / 5	ASP A 109 PHE A 97 ASN A 29 TYR A 35	None	1.19A	6a93B-2rbdA: 2.3	6a93B-2rbdA: 19.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRK_A_TFPA204_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2rbd","BH2358 PROTEIN","Bacillus halodurans",5,"PHE A 136;LEU A  69;PHE A 133;MET A 132;LEU A  25","None","1.36A","1wrkA-2rbdA:undetectable;1wrkB-2rbdA:undetectable","1wrkA-2rbdA:16.77;1wrkB-2rbdA:16.77"],["1ZLQ_A_ACTA1507_0","NICKEL-BINDING PERIPLASMIC PROTEIN","2rbd","BH2358 PROTEIN","Bacillus halodurans",3,"GLN A 123;HIS A  14;ARG A 126","None","0.95A","1zlqA-2rbdA:undetectable","1zlqA-2rbdA:14.60"],["5X7P_A_ACRA1431_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","2rbd","BH2358 PROTEIN","Bacillus halodurans",4,"ASN A 153;ASP A  46;TRP A 156;GLY A  43","None","1.14A","5x7pA-2rbdA:undetectable","5x7pA-2rbdA:8.64"],["6A93_B_8NUB3001_1","5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562","2rbd","BH2358 PROTEIN","Bacillus halodurans",4,"ASP A 109;PHE A  97;ASN A  29;TYR A  35","None","1.19A","6a93B-2rbdA:2.3","6a93B-2rbdA:19.36"]]