SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2rbg PUTATIVE
UNCHARACTERIZED
PROTEIN ST0493
(Sulfurisphaera
tokodaii) 		3 / 3 ILE A  24
ILE A  53
LEU A 125
 None
 0.57A 2prgA-2rbgA:
undetectable		 2prgA-2rbgA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 2rbg PUTATIVE
UNCHARACTERIZED
PROTEIN ST0493
(Sulfurisphaera
tokodaii) 		5 / 9 LEU A   7
ILE A  24
ILE A  53
PHE A  41
VAL A  40
 None
 1.32A 3tmzA-2rbgA:
undetectable		 3tmzA-2rbgA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 2rbg PUTATIVE
UNCHARACTERIZED
PROTEIN ST0493
(Sulfurisphaera
tokodaii) 		4 / 7 PHE A  25
ASP A  27
THR A   8
ILE A  10
 None
 0.79A 4pcuA-2rbgA:
2.3		 4pcuA-2rbgA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2rbg PUTATIVE
UNCHARACTERIZED
PROTEIN ST0493
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A  69
ILE A  38
ILE A  44
ILE A  53
PHE A  17
 None
 1.25A 4rp8C-2rbgA:
undetectable		 4rp8C-2rbgA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 2rbg PUTATIVE
UNCHARACTERIZED
PROTEIN ST0493
(Sulfurisphaera
tokodaii) 		6 / 12 PHE A  17
ILE A  53
ILE A  38
ASN A  39
LEU A  49
VAL A  12
 None
 1.43A 5uvmB-2rbgA:
undetectable		 5uvmB-2rbgA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 2rbg PUTATIVE
UNCHARACTERIZED
PROTEIN ST0493
(Sulfurisphaera
tokodaii) 		5 / 12 PHE A  17
ILE A  53
ILE A  38
ASN A  39
VAL A  12
 None
 0.96A 5uvmB-2rbgA:
undetectable		 5uvmB-2rbgA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 2rbg PUTATIVE
UNCHARACTERIZED
PROTEIN ST0493
(Sulfurisphaera
tokodaii) 		5 / 12 PHE A  17
VAL A  28
PHE A  78
PHE A  41
PHE A  25
 None
 1.45A 6becA-2rbgA:
undetectable
6becB-2rbgA:
undetectable
6becC-2rbgA:
undetectable		 6becA-2rbgA:
14.88
6becB-2rbgA:
14.88
6becC-2rbgA:
14.88