SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		4 / 8 THR A 410
THR A 260
LEU A 350
VAL A 386
 None
 0.85A 1t86A-2rd7A:
undetectable		 1t86A-2rd7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_B_LNRB200_1
(D7R4 PROTEIN)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		5 / 10 GLU A 322
ILE A 324
ARG A 392
TYR A 200
ASP A 242
 None
 1.43A 2qeoB-2rd7A:
undetectable		 2qeoB-2rd7A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		3 / 3 GLY A 373
GLY A 375
THR A 377
 None
 0.34A 3si7B-2rd7A:
undetectable		 3si7B-2rd7A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		4 / 8 THR A 410
THR A 260
LEU A 350
VAL A 386
 None
 0.89A 4l4aA-2rd7A:
undetectable		 4l4aA-2rd7A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		4 / 8 THR A 410
THR A 260
LEU A 350
VAL A 386
 None
 0.74A 4l4eA-2rd7A:
undetectable		 4l4eA-2rd7A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		4 / 8 THR A 410
THR A 260
LEU A 350
VAL A 386
 None
 0.77A 4l4fA-2rd7A:
undetectable		 4l4fA-2rd7A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		5 / 12 LEU A 129
GLY A 308
HIS A 310
MET A 431
PHE A 429
 None
 1.42A 4pfjB-2rd7A:
undetectable		 4pfjB-2rd7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		5 / 12 LEU A 129
GLY A 308
HIS A 310
MET A 431
PHE A 429
 None
 1.38A 4pgfA-2rd7A:
undetectable		 4pgfA-2rd7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		4 / 8 THR A 260
PHE A 372
PHE A 199
ILE A 337
 None
 1.02A 5vkqB-2rd7A:
undetectable
5vkqC-2rd7A:
undetectable		 5vkqB-2rd7A:
10.82
5vkqC-2rd7A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		5 / 12 LEU A 129
GLY A 308
HIS A 310
MET A 431
PHE A 429
 None
 1.45A 6aphA-2rd7A:
undetectable		 6aphA-2rd7A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		3 / 3 VAL A 386
GLU A 387
ILE A 342
 None
 0.63A 6f7lB-2rd7A:
undetectable		 6f7lB-2rd7A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		5 / 12 LEU A 129
GLY A 308
HIS A 310
MET A 431
PHE A 429
 None
 1.31A 6gbnB-2rd7A:
undetectable		 6gbnB-2rd7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 2rd7 COMPLEMENT COMPONENT
C8 ALPHA CHAIN
(Homo
sapiens) 		4 / 5 ASN A 181
TYR A 307
GLY A 308
ASP A 281
 None
 1.29A 6gh9A-2rd7A:
undetectable		 6gh9A-2rd7A:
14.61