SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 2rd9 BH0186 PROTEIN
(Bacillus
halodurans) 		5 / 10 LEU A  65
LEU A  61
SER A 137
LEU A 136
ARG A 120
 None
 1.22A 2ceoB-2rd9A:
undetectable		 2ceoB-2rd9A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 2rd9 BH0186 PROTEIN
(Bacillus
halodurans) 		5 / 9 ILE A  64
GLY A 122
SER A 137
LEU A 136
LEU A 118
 None
None
None
None
IMD  A 302 ( 4.9A)
 1.08A 3ai9X-2rd9A:
undetectable		 3ai9X-2rd9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 2rd9 BH0186 PROTEIN
(Bacillus
halodurans) 		5 / 9 LEU A 135
ILE A  64
GLY A 122
SER A 137
LEU A 118
 None
None
None
None
IMD  A 302 ( 4.9A)
 1.07A 3ai9X-2rd9A:
undetectable		 3ai9X-2rd9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2rd9 BH0186 PROTEIN
(Bacillus
halodurans) 		4 / 8 ASN A 104
THR A 107
LEU A 111
ARG A  62
 None
 1.04A 3kp2A-2rd9A:
undetectable
3kp2B-2rd9A:
undetectable		 3kp2A-2rd9A:
20.92
3kp2B-2rd9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_2
(ADENOSYLHOMOCYSTEINA
SE)		 2rd9 BH0186 PROTEIN
(Bacillus
halodurans) 		4 / 4 GLU A  38
THR A  39
GLU A  44
HIS A  81
 None
None
GOL  A 304 (-3.5A)
None
 1.45A 5utuF-2rd9A:
0.1		 5utuF-2rd9A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2rd9 BH0186 PROTEIN
(Bacillus
halodurans) 		3 / 3 HIS A  48
HIS A 142
HIS A 146
 NI  A 300 (-3.3A)
NI  A 300 ( 3.2A)
NI  A 300 ( 3.4A)
 0.58A 6giqa-2rd9A:
2.5		 6giqa-2rd9A:
15.46