SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rdc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_A_1N1A2000_1 (P38A)	2rdc	UNCHARACTERIZED PROTEIN (Geobacter sulfurreducens)	5 / 12	ILE A 30 ARG A 25 TRP A 138 MET A 23 ILE A 133	None CL A 153 (-3.3A) None None None	1.17A	3ohtA-2rdcA: 1.9 3ohtB-2rdcA: 2.2	3ohtA-2rdcA: 16.03 3ohtB-2rdcA: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_B_1N1B2000_1 (P38A)	2rdc	UNCHARACTERIZED PROTEIN (Geobacter sulfurreducens)	5 / 10	ARG A 132 ILE A 30 ARG A 25 TRP A 138 MET A 23	None None CL A 153 (-3.3A) None None	1.41A	3ohtA-2rdcA: undetectable 3ohtB-2rdcA: 2.2	3ohtA-2rdcA: 16.03 3ohtB-2rdcA: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_B_1N1B2000_1 (P38A)	2rdc	UNCHARACTERIZED PROTEIN (Geobacter sulfurreducens)	5 / 10	ILE A 133 ILE A 30 ARG A 25 TRP A 138 MET A 23	None None CL A 153 (-3.3A) None None	1.18A	3ohtA-2rdcA: undetectable 3ohtB-2rdcA: 2.2	3ohtA-2rdcA: 16.03 3ohtB-2rdcA: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4COX_C_IMNC701_1 (CYCLOOXYGENASE-2)	2rdc	UNCHARACTERIZED PROTEIN (Geobacter sulfurreducens)	6 / 12	ARG A 52 LEU A 98 SER A 96 TRP A 138 GLY A 50 ALA A 49	None	1.23A	4coxC-2rdcA: undetectable	4coxC-2rdcA: 12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_B_CELB602_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2rdc	UNCHARACTERIZED PROTEIN (Geobacter sulfurreducens)	5 / 12	ARG A 52 LEU A 98 TRP A 138 GLY A 50 ALA A 49	None	1.00A	5jw1B-2rdcA: undetectable	5jw1B-2rdcA: 13.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OHT_A_1N1A2000_1","P38A;P38A","2rdc","UNCHARACTERIZED PROTEIN","Geobacter sulfurreducens",5,"ILE A  30;ARG A  25;TRP A 138;MET A  23;ILE A 133","None; CL A 153 (-3.3A);None;None;None","1.17A","3ohtA-2rdcA:1.9;3ohtB-2rdcA:2.2","3ohtA-2rdcA:16.03;3ohtB-2rdcA:16.03"],["3OHT_B_1N1B2000_1","P38A;P38A","2rdc","UNCHARACTERIZED PROTEIN","Geobacter sulfurreducens",5,"ARG A 132;ILE A  30;ARG A  25;TRP A 138;MET A  23","None;None; CL A 153 (-3.3A);None;None","1.41A","3ohtA-2rdcA:undetectable;3ohtB-2rdcA:2.2","3ohtA-2rdcA:16.03;3ohtB-2rdcA:16.03"],["3OHT_B_1N1B2000_1","P38A;P38A","2rdc","UNCHARACTERIZED PROTEIN","Geobacter sulfurreducens",5,"ILE A 133;ILE A  30;ARG A  25;TRP A 138;MET A  23","None;None; CL A 153 (-3.3A);None;None","1.18A","3ohtA-2rdcA:undetectable;3ohtB-2rdcA:2.2","3ohtA-2rdcA:16.03;3ohtB-2rdcA:16.03"],["4COX_C_IMNC701_1","CYCLOOXYGENASE-2","2rdc","UNCHARACTERIZED PROTEIN","Geobacter sulfurreducens",6,"ARG A  52;LEU A  98;SER A  96;TRP A 138;GLY A  50;ALA A  49","None","1.23A","4coxC-2rdcA:undetectable","4coxC-2rdcA:12.84"],["5JW1_B_CELB602_1","PROSTAGLANDIN G\/H SYNTHASE 2","2rdc","UNCHARACTERIZED PROTEIN","Geobacter sulfurreducens",5,"ARG A  52;LEU A  98;TRP A 138;GLY A  50;ALA A  49","None","1.00A","5jw1B-2rdcA:undetectable","5jw1B-2rdcA:13.69"]]