SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2re3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		5 / 12 LEU A  79
VAL A 117
ALA A  45
PHE A  51
VAL A  63
 None
 1.45A 2g72A-2re3A:
undetectable		 2g72A-2re3A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 5 LEU A 175
GLY A 166
MET A 185
PHE A 159
 None
 1.09A 3uq6B-2re3A:
undetectable		 3uq6B-2re3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 4 LEU A 175
GLY A 166
MET A 185
PHE A 159
 None
 1.13A 3vaqB-2re3A:
undetectable		 3vaqB-2re3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		3 / 3 LYS A  85
PRO A  34
LYS A  71
 None
 1.36A 4duzL-2re3A:
undetectable		 4duzL-2re3A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		3 / 3 LYS A  85
PRO A  34
LYS A  71
 None
 1.30A 4dv7L-2re3A:
undetectable		 4dv7L-2re3A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 PHE A  66
ARG A  64
ALA A  61
LEU A  65
 None
 1.05A 4rkuA-2re3A:
undetectable
4rkuJ-2re3A:
undetectable		 4rkuA-2re3A:
13.45
4rkuJ-2re3A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		3 / 3 VAL A  80
PHE A  36
ARG A  76
 None
 0.90A 4xr4B-2re3A:
undetectable		 4xr4B-2re3A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		5 / 10 ILE A  88
LEU A  70
PHE A  77
GLY A  48
ALA A  45
 None
 1.12A 5mxbA-2re3A:
undetectable		 5mxbA-2re3A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 4 VAL A  96
GLY A  48
ASP A  47
ASP A  91
 None
 1.36A 6cjkC-2re3A:
undetectable		 6cjkC-2re3A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 6 PHE A  95
VAL A  63
LEU A  79
LEU A  70
 None
 0.95A 6e43A-2re3A:
undetectable		 6e43A-2re3A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 6 PHE A  95
VAL A  63
LEU A  79
LEU A  70
 None
 0.96A 6e43B-2re3A:
undetectable		 6e43B-2re3A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 6 PHE A  95
VAL A  63
LEU A  79
LEU A  70
 None
 0.95A 6e43C-2re3A:
undetectable		 6e43C-2re3A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 6 PHE A  95
VAL A  63
LEU A  79
LEU A  70
 None
 0.98A 6e43D-2re3A:
undetectable		 6e43D-2re3A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 2re3 UNCHARACTERIZED
PROTEIN
(Ruegeria
pomeroyi) 		4 / 6 ASN A  37
VAL A  86
VAL A  80
THR A  81
 None
None
None
GOL  A 194 ( 4.5A)
 1.21A 6f32B-2re3A:
undetectable		 6f32B-2re3A:
18.64