SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2re7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 2re7 UNCHARACTERIZED
PROTEIN
(Psychrobacter
arcticus) 		3 / 3 ALA A  87
VAL A 123
TRP A  49
 None
 0.96A 1grmA-2re7A:
undetectable		 1grmA-2re7A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 2re7 UNCHARACTERIZED
PROTEIN
(Psychrobacter
arcticus) 		3 / 3 ALA A  87
VAL A 123
TRP A  49
 None
 0.96A 1grmB-2re7A:
undetectable		 1grmB-2re7A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 2re7 UNCHARACTERIZED
PROTEIN
(Psychrobacter
arcticus) 		5 / 12 SER A  39
MET A  36
PRO A  35
ALA A  33
ILE A  22
 None
 1.40A 1s14B-2re7A:
undetectable		 1s14B-2re7A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2re7 UNCHARACTERIZED
PROTEIN
(Psychrobacter
arcticus) 		4 / 5 LEU A  70
GLY A  52
ALA A  20
ILE A  22
 None
 0.75A 2aohB-2re7A:
undetectable		 2aohB-2re7A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2re7 UNCHARACTERIZED
PROTEIN
(Psychrobacter
arcticus) 		5 / 10 ILE A  68
VAL A 122
ILE A  48
ILE A  83
SER A  82
 None
 1.18A 3kpbD-2re7A:
undetectable		 3kpbD-2re7A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2re7 UNCHARACTERIZED
PROTEIN
(Psychrobacter
arcticus) 		5 / 12 ILE A  68
VAL A 122
ILE A  48
ILE A  83
SER A  82
 None
 1.03A 3kpdC-2re7A:
undetectable		 3kpdC-2re7A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2re7 UNCHARACTERIZED
PROTEIN
(Psychrobacter
arcticus) 		3 / 3 VAL A 127
GLU A 128
ILE A  83
 SO4  A 135 (-4.6A)
None
None
 0.65A 6f7lB-2re7A:
undetectable		 6f7lB-2re7A:
11.06