SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ree'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2ree CURA
(Moorea
producens) 		4 / 6 LEU A 339
GLN A 340
PHE A 337
LEU A 316
 None
 0.97A 3ag1C-2reeA:
undetectable
3ag1J-2reeA:
undetectable		 3ag1C-2reeA:
20.86
3ag1J-2reeA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 2ree CURA
(Moorea
producens) 		5 / 12 GLY A 414
LEU A 400
PRO A 304
LEU A 305
VAL A 354
 None
 0.93A 3av6A-2reeA:
undetectable		 3av6A-2reeA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 2ree CURA
(Moorea
producens) 		5 / 8 GLY A 414
VAL A 417
ALA A 394
ASP A 383
LEU A 381
 None
 1.21A 4l9iB-2reeA:
undetectable		 4l9iB-2reeA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ree CURA
(Moorea
producens) 		4 / 6 GLN A 271
THR A 355
HIS A 389
ASN A 320
 None
None
None
GOL  A 601 ( 4.6A)
 1.30A 4pfjB-2reeA:
undetectable		 4pfjB-2reeA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2ree CURA
(Moorea
producens) 		5 / 12 ILE A 273
GLN A 269
TYR A 285
ILE A 284
ALA A 283
 None
 0.90A 5n0sB-2reeA:
undetectable		 5n0sB-2reeA:
18.36