SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2reu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		4 / 7 ILE A 197
PHE A 143
PHE A 122
PHE A  89
 None
 1.21A 1e71M-2reuA:
undetectable		 1e71M-2reuA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		4 / 7 ILE A 197
PHE A 143
PHE A 122
PHE A  89
 None
 1.22A 1e72M-2reuA:
undetectable		 1e72M-2reuA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		3 / 3 LEU A 218
TRP A 237
GLY A 211
 None
 0.71A 3l35A-2reuA:
undetectable
3l35H-2reuA:
undetectable		 3l35A-2reuA:
10.85
3l35H-2reuA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		3 / 3 LEU A 218
TRP A 237
GLY A 211
 None
 0.71A 3l35B-2reuA:
undetectable
3l35K-2reuA:
undetectable		 3l35B-2reuA:
10.85
3l35K-2reuA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		4 / 5 PHE A 143
ILE A 140
ASN A 246
PHE A 142
 None
 1.41A 3octA-2reuA:
undetectable		 3octA-2reuA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		4 / 4 ILE A 222
LEU A 218
LYS A 220
ASN A 223
 None
 1.32A 4g19D-2reuA:
0.0		 4g19D-2reuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		4 / 7 ARG A 184
PRO A 228
SER A 230
VAL A 174
 None
 1.11A 4klrA-2reuA:
undetectable		 4klrA-2reuA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		3 / 3 ASP A 195
ARG A 156
PRO A 153
 None
 1.01A 4wanC-2reuA:
undetectable		 4wanC-2reuA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 2reu TYPE II RESTRICTION
ENZYME SAU3AI
(Staphylococcus
aureus) 		4 / 5 ASP A 135
TYR A  40
LEU A  38
THR A  74
 None
 1.25A 4wozF-2reuA:
undetectable
4wozH-2reuA:
undetectable		 4wozF-2reuA:
23.68
4wozH-2reuA:
23.68