SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rf0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2rf0 MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 10
(Homo
sapiens) 		5 / 10 VAL A  45
VAL A  43
LEU A  37
GLY A  61
GLY A  69
 None
 1.32A 3ls4H-2rf0A:
undetectable		 3ls4H-2rf0A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2rf0 MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 10
(Homo
sapiens) 		4 / 7 VAL A  43
VAL A  45
LEU A  46
VAL A  52
 None
 1.04A 4e1gB-2rf0A:
undetectable		 4e1gB-2rf0A:
9.68