SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rff'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 2rff PUTATIVE
NUCLEOTIDYLTRANSFERA
SE
(Sulfolobus
solfataricus) 		4 / 5 PHE A  56
PHE A  29
PHE A  58
VAL A  73
 None
 1.06A 5a1rA-2rffA:
undetectable		 5a1rA-2rffA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 2rff PUTATIVE
NUCLEOTIDYLTRANSFERA
SE
(Sulfolobus
solfataricus) 		4 / 6 GLY A  44
SER A  40
TYR A  46
GLY A  39
 None
 0.81A 5k4pA-2rffA:
undetectable		 5k4pA-2rffA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 2rff PUTATIVE
NUCLEOTIDYLTRANSFERA
SE
(Sulfolobus
solfataricus) 		5 / 9 ILE A  54
ILE A  77
GLU A  34
VAL A  22
ILE A  21
 None
 1.20A 6hloA-2rffA:
undetectable		 6hloA-2rffA:
15.13