SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rh7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		5 / 12 ALA A  64
PHE A 124
MET A  29
PHE A 165
LEU A 200
 None
None
None
None
CRO  A  66 ( 4.2A)
 1.19A 1dtlA-2rh7A:
undetectable		 1dtlA-2rh7A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		4 / 8 ILE A  46
VAL A 107
MET A  29
GLY A  31
 None
 0.74A 1dzmA-2rh7A:
2.7		 1dzmA-2rh7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		3 / 3 LYS A 202
ASP A 101
ASP A  59
 None
 0.98A 2br4D-2rh7A:
undetectable		 2br4D-2rh7A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		4 / 7 TYR A 181
THR A 179
VAL A  63
VAL A 122
 None
None
CRO  A  66 ( 3.9A)
None
 0.97A 2qbnA-2rh7A:
undetectable		 2qbnA-2rh7A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		3 / 3 PHE A 118
ASN A  69
PHE A  91
 None
CRO  A  66 ( 4.8A)
None
 0.87A 2zbuD-2rh7A:
undetectable		 2zbuD-2rh7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		5 / 9 ALA A  57
LEU A 129
VAL A  22
ILE A  97
PHE A 124
 None
 1.22A 3freX-2rh7A:
undetectable		 3freX-2rh7A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		5 / 11 ALA A  57
LEU A 129
VAL A  22
ILE A  97
PHE A 124
 None
 1.22A 3jw5A-2rh7A:
undetectable		 3jw5A-2rh7A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		5 / 11 PHE A  87
LEU A 113
TYR A  72
LEU A   8
ILE A  37
 None
 1.32A 3o94A-2rh7A:
undetectable		 3o94A-2rh7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		5 / 11 PHE A  87
LEU A 113
TYR A  72
LEU A   8
ILE A  37
 None
 1.32A 3o94C-2rh7A:
undetectable		 3o94C-2rh7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		5 / 11 PHE A  87
LEU A 113
TYR A  72
LEU A   8
ILE A  37
 None
 1.32A 3o94D-2rh7A:
undetectable		 3o94D-2rh7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		3 / 3 PRO A 191
MET A 190
TYR A  82
 None
 0.71A 4qa0B-2rh7A:
undetectable		 4qa0B-2rh7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		3 / 3 PRO A 191
MET A 190
TYR A  82
 None
 0.73A 4qa0A-2rh7A:
undetectable		 4qa0A-2rh7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		3 / 3 PRO A 191
MET A 190
TYR A  82
 None
 0.81A 4qa2B-2rh7A:
undetectable		 4qa2B-2rh7A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		3 / 3 LYS A 116
PRO A  13
LYS A  15
 None
 1.16A 5y9yA-2rh7A:
undetectable		 5y9yA-2rh7A:
22.09