SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rhm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		4 / 7 THR A  18
ALA A  14
THR A  15
ALA A 112
 CL  A 193 (-4.2A)
None
None
None
 1.04A 4qw0K-2rhmA:
undetectable		 4qw0K-2rhmA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		4 / 7 THR A  18
ALA A  14
THR A  15
ALA A 112
 CL  A 193 (-4.2A)
None
None
None
 1.03A 4qw0Y-2rhmA:
undetectable		 4qw0Y-2rhmA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		5 / 10 ILE A   8
ILE A   7
LEU A  24
ILE A 152
ASN A  84
 None
 0.95A 5vkqA-2rhmA:
undetectable
5vkqD-2rhmA:
undetectable		 5vkqA-2rhmA:
8.11
5vkqD-2rhmA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		5 / 10 ILE A 152
ASN A  84
ILE A   8
ILE A   7
LEU A  24
 None
 0.95A 5vkqA-2rhmA:
undetectable
5vkqB-2rhmA:
undetectable		 5vkqA-2rhmA:
8.11
5vkqB-2rhmA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		5 / 10 ILE A 152
ASN A  84
ILE A   8
ILE A   7
LEU A  24
 None
 0.95A 5vkqC-2rhmA:
undetectable
5vkqD-2rhmA:
undetectable		 5vkqC-2rhmA:
8.11
5vkqD-2rhmA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		4 / 5 TYR A  66
MET A  94
THR A  91
LEU A 157
 None
 1.30A 5x1bJ-2rhmA:
undetectable		 5x1bJ-2rhmA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		4 / 5 TYR A  66
MET A  94
THR A  91
LEU A 157
 None
 1.27A 5x1bW-2rhmA:
undetectable		 5x1bW-2rhmA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		4 / 6 LEU A  65
ALA A  61
LEU A  32
SER A  83
 None
 0.90A 6f88B-2rhmA:
undetectable		 6f88B-2rhmA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2rhm PUTATIVE KINASE
(Chloroflexus
aurantiacus) 		4 / 5 TYR A  66
ARG A  93
MET A  94
THR A  91
 None
 1.39A 6nknW-2rhmA:
undetectable		 6nknW-2rhmA:
13.47