SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rhp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 PRO A 906
ASP A 903
ASP A 900
 None
CA  A1174 ( 2.5A)
CA  A   8 (-2.3A)
 0.76A 1sqfA-2rhpA:
undetectable		 1sqfA-2rhpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 ASP A 806
ASN A 810
GLY A 805
ASP A 791
ASP A 797
 CA  A  20 ( 2.7A)
None
None
CA  A  16 (-2.7A)
None
 1.48A 2fqyA-2rhpA:
undetectable		 2fqyA-2rhpA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 6 TYR A1122
TYR A1141
GLY A1138
ASP A1136
 None
 1.14A 2g72A-2rhpA:
undetectable		 2g72A-2rhpA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 ASP A 822
ASP A 806
ASP A 825
 None
CA  A  20 ( 2.7A)
CA  A  18 (-3.4A)
 0.76A 2igtB-2rhpA:
undetectable		 2igtB-2rhpA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 6 SER A 994
PRO A 966
GLY A 997
TRP A 979
 None
 1.23A 2y7pA-2rhpA:
undetectable		 2y7pA-2rhpA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_C_GLYC73_0
(NONSTRUCTURAL
PROTEIN 1)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 4 ASP A 863
ASP A 852
SER A1033
ARG A1036
 CA  A  10 (-3.1A)
CA  A  12 ( 2.6A)
None
NAG  A   4 ( 3.8A)
 1.49A 2z0aC-2rhpA:
undetectable		 2z0aC-2rhpA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A1023
SER A1156
GLU A1051
ASP A1052
 CA  A  15 ( 2.5A)
CA  A  13 (-2.3A)
None
None
 1.02A 3bc9A-2rhpA:
undetectable		 3bc9A-2rhpA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 VAL A1160
LEU A1152
TRP A1112
VAL A1028
 None
 0.91A 3hs6B-2rhpA:
0.7		 3hs6B-2rhpA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 5 ASP A 899
ASP A 903
ASP A 910
ARG A 909
 CA  A1174 ( 3.1A)
CA  A1174 ( 2.5A)
CA  A1175 ( 2.5A)
None
 1.43A 3naiC-2rhpA:
undetectable		 3naiC-2rhpA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 9 ARG A 982
ILE A 981
LEU A1152
LEU A 723
GLY A1012
 None
 1.48A 3nxuB-2rhpA:
undetectable		 3nxuB-2rhpA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 11 ASP A 939
ASP A 937
HIS A 887
ILE A 954
SER A 955
 CA  A1173 ( 2.9A)
CA  A   2 ( 2.6A)
None
None
CA  A1173 (-2.9A)
 1.01A 3o94A-2rhpA:
undetectable		 3o94A-2rhpA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 11 ASP A 939
ASP A 937
HIS A 887
ILE A 954
SER A 955
 CA  A1173 ( 2.9A)
CA  A   2 ( 2.6A)
None
None
CA  A1173 (-2.9A)
 1.02A 3o94B-2rhpA:
undetectable		 3o94B-2rhpA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 11 ASP A 939
ASP A 937
HIS A 887
ILE A 954
SER A 955
 CA  A1173 ( 2.9A)
CA  A   2 ( 2.6A)
None
None
CA  A1173 (-2.9A)
 1.02A 3o94C-2rhpA:
undetectable		 3o94C-2rhpA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 11 ASP A 939
ASP A 937
HIS A 887
ILE A 954
SER A 955
 CA  A1173 ( 2.9A)
CA  A   2 ( 2.6A)
None
None
CA  A1173 (-2.9A)
 1.01A 3o94D-2rhpA:
undetectable		 3o94D-2rhpA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 TYR A 819
GLY A 805
ASP A 802
 None
None
CA  A  20 (-3.1A)
 0.61A 3ou6C-2rhpA:
undetectable		 3ou6C-2rhpA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 TYR A 878
ASP A 874
ASP A 866
 None
CA  A   9 ( 2.3A)
NAG  A   4 (-3.7A)
 1.00A 3ou7B-2rhpA:
undetectable		 3ou7B-2rhpA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 ASP A 738
ASP A 741
GLY A 748
ASP A 747
ASP A 734
 None
CA  A  26 (-2.3A)
None
CA  A  24 ( 3.1A)
CA  A  26 ( 2.8A)
 1.01A 3prsA-2rhpA:
undetectable		 3prsA-2rhpA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 930
ASP A 922
GLY A 927
ARG A 609
 CA  A   3 (-3.1A)
CA  A   3 (-3.5A)
None
None
 0.92A 3s3nA-2rhpA:
undetectable		 3s3nA-2rhpA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SDR_A_210A822_1
(ALPHA-BISABOLENE
SYNTHASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 4 ASP A 924
ASP A 922
ARG A 625
ASP A 673
 CA  A   3 (-3.0A)
CA  A   3 (-3.5A)
None
None
 1.32A 3sdrA-2rhpA:
0.0		 3sdrA-2rhpA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SDV_A_911A822_0
(ALPHA-BISABOLENE
SYNTHASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 4 ASP A 924
ASP A 922
ARG A 625
ASP A 673
 CA  A   3 (-3.0A)
CA  A   3 (-3.5A)
None
None
 1.32A 3sdvA-2rhpA:
0.0		 3sdvA-2rhpA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 GLN A 728
GLY A 727
VAL A 980
GLY A 699
ALA A1109
 None
 1.03A 3sudD-2rhpA:
undetectable		 3sudD-2rhpA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 GLN A 728
GLY A 727
VAL A 980
GLY A 699
ALA A1109
 None
 1.07A 3sueC-2rhpA:
undetectable		 3sueC-2rhpA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 PHE A1005
HIS A1116
GLY A1006
GLY A1151
 None
 0.99A 3v3nC-2rhpA:
undetectable		 3v3nC-2rhpA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 TRP A1042
VAL A1045
TRP A1104
 None
 0.92A 3zq8C-2rhpA:
undetectable
3zq8D-2rhpA:
undetectable		 3zq8C-2rhpA:
2.70
3zq8D-2rhpA:
2.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 ASN A 784
ASP A 777
ASN A 778
 CA  A  21 (-3.1A)
CA  A  21 ( 2.4A)
None
 0.79A 4agaA-2rhpA:
undetectable		 4agaA-2rhpA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 ASN A 881
ASP A 874
ASN A 875
 CA  A   9 (-3.3A)
CA  A   9 ( 2.3A)
None
 0.80A 4agaA-2rhpA:
undetectable		 4agaA-2rhpA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 7 ASP A 738
ASP A 734
ASP A 754
ASN A 746
ASP A 743
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
CA  A  24 ( 3.3A)
 1.47A 4feuB-2rhpA:
undetectable		 4feuB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 7 ASP A 894
ASP A 890
ASP A 910
ASN A 902
ASP A 899
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
CA  A1174 ( 3.1A)
 1.48A 4feuB-2rhpA:
undetectable		 4feuB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 903
ASP A 894
ASP A 886
ASP A 907
 CA  A1174 ( 2.5A)
None
CA  A   7 (-3.1A)
CA  A   8 (-3.1A)
 1.08A 4feuD-2rhpA:
undetectable		 4feuD-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 673
ASP A 922
GLU A 649
ASP A 924
 None
CA  A   3 (-3.5A)
None
CA  A   3 (-3.0A)
 1.20A 4feuF-2rhpA:
undetectable		 4feuF-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.21A 4fevB-2rhpA:
undetectable		 4fevB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.11A 4fevD-2rhpA:
undetectable		 4fevD-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.14A 4fevD-2rhpA:
undetectable		 4fevD-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.11A 4fevF-2rhpA:
undetectable		 4fevF-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.15A 4fevF-2rhpA:
undetectable		 4fevF-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.16A 4fewB-2rhpA:
undetectable		 4fewB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.19A 4fewB-2rhpA:
undetectable		 4fewB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.10A 4fewD-2rhpA:
undetectable		 4fewD-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.13A 4fewD-2rhpA:
undetectable		 4fewD-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.13A 4fewF-2rhpA:
undetectable		 4fewF-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.16A 4fewF-2rhpA:
undetectable		 4fewF-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 673
ASP A 922
GLU A 649
ASP A 924
 None
CA  A   3 (-3.5A)
None
CA  A   3 (-3.0A)
 1.21A 4fexB-2rhpA:
undetectable		 4fexB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.13A 4fexB-2rhpA:
undetectable		 4fexB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.16A 4fexB-2rhpA:
undetectable		 4fexB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.09A 4gkhB-2rhpA:
undetectable		 4gkhB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.12A 4gkhB-2rhpA:
undetectable		 4gkhB-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.20A 4gkhD-2rhpA:
undetectable		 4gkhD-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.12A 4gkhF-2rhpA:
undetectable		 4gkhF-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.15A 4gkhF-2rhpA:
undetectable		 4gkhF-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.12A 4gkhG-2rhpA:
undetectable		 4gkhG-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.16A 4gkhG-2rhpA:
undetectable		 4gkhG-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 6 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.17A 4gkhJ-2rhpA:
undetectable		 4gkhJ-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 6 ASP A 738
ASP A 734
ASP A 754
ASP A 743
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  24 ( 3.3A)
 1.34A 4gkhJ-2rhpA:
undetectable		 4gkhJ-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 6 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.20A 4gkhJ-2rhpA:
undetectable		 4gkhJ-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 6 ASP A 894
ASP A 890
ASP A 910
ASP A 899
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1174 ( 3.1A)
 1.29A 4gkhJ-2rhpA:
undetectable		 4gkhJ-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.10A 4gkhC-2rhpA:
undetectable
4gkhK-2rhpA:
undetectable		 4gkhC-2rhpA:
17.61
4gkhK-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.14A 4gkhC-2rhpA:
undetectable
4gkhK-2rhpA:
undetectable		 4gkhC-2rhpA:
17.61
4gkhK-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.11A 4gkiA-2rhpA:
undetectable		 4gkiA-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.15A 4gkiA-2rhpA:
undetectable		 4gkiA-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 673
ASP A 922
GLU A 649
ASP A 924
 None
CA  A   3 (-3.5A)
None
CA  A   3 (-3.0A)
 1.16A 4gkiC-2rhpA:
undetectable		 4gkiC-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.14A 4gkiC-2rhpA:
undetectable		 4gkiC-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 894
ASP A 890
ASP A 910
ASN A 902
 None
CA  A   7 ( 2.5A)
CA  A1175 ( 2.5A)
CA  A1176 (-3.1A)
 1.17A 4gkiC-2rhpA:
undetectable		 4gkiC-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A 738
ASP A 734
ASP A 754
ASN A 746
 None
CA  A  26 ( 2.8A)
CA  A  23 ( 2.3A)
CA  A  26 (-2.7A)
 1.12A 4gkiE-2rhpA:
undetectable
4gkiG-2rhpA:
undetectable		 4gkiE-2rhpA:
17.61
4gkiG-2rhpA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 VAL A1028
TYR A1031
LEU A1078
LEU A1082
 None
 1.09A 4jtrA-2rhpA:
undetectable		 4jtrA-2rhpA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ASP A 939
PRO A 942
ASP A 946
SER A 955
 CA  A1173 ( 2.9A)
None
CA  A1173 ( 2.1A)
CA  A1173 (-2.9A)
 1.27A 4k7gB-2rhpA:
undetectable		 4k7gB-2rhpA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 6 ASP A 937
ASN A 883
TYR A1167
ASP A 946
 CA  A   2 ( 2.6A)
None
None
CA  A1173 ( 2.1A)
 1.05A 4mdaA-2rhpA:
undetectable		 4mdaA-2rhpA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 ASP A 718
ASP A 696
ASN A1017
 CA  A  29 ( 2.3A)
CA  A  28 ( 2.6A)
None
 0.70A 4q5mA-2rhpA:
undetectable		 4q5mA-2rhpA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 GLY A1073
PHE A1155
ALA A1081
GLN A1091
HIS A1077
 None
 1.30A 4wh5A-2rhpA:
undetectable		 4wh5A-2rhpA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQL_A_KANA203_1
(2''-AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 9 ASP A 935
ASP A 939
ASP A 937
TYR A1167
GLU A1168
 CA  A   2 (-3.2A)
CA  A1173 ( 2.9A)
CA  A   2 ( 2.6A)
None
None
 1.35A 4wqlA-2rhpA:
0.0		 4wqlA-2rhpA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A1022
ASP A1021
ASP A1023
ILE A 975
 CA  A  15 (-3.1A)
CA  A  13 (-2.4A)
CA  A  15 ( 2.5A)
None
 0.99A 4xjeA-2rhpA:
undetectable		 4xjeA-2rhpA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 GLU A 795
GLY A 796
TYR A 781
ILE A 803
ILE A 788
 None
CA  A  16 ( 4.7A)
None
None
None
 1.45A 4xucA-2rhpA:
undetectable		 4xucA-2rhpA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 GLU A 795
GLY A 796
TYR A 781
ILE A 803
ILE A 788
 None
CA  A  16 ( 4.7A)
None
None
None
 1.48A 4xudA-2rhpA:
undetectable		 4xudA-2rhpA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 8 ASP A1022
ASP A1021
ASP A1023
ILE A 975
 CA  A  15 (-3.1A)
CA  A  13 (-2.4A)
CA  A  15 ( 2.5A)
None
 1.01A 5cfsA-2rhpA:
undetectable		 5cfsA-2rhpA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 4 ASP A 754
GLY A 748
ASP A 743
ASP A 738
 CA  A  23 ( 2.3A)
None
CA  A  24 ( 3.3A)
None
 1.07A 5e72A-2rhpA:
undetectable		 5e72A-2rhpA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		3 / 3 ARG A1093
THR A1144
ASP A1142
 None
NAG  A   4 (-4.3A)
None
 0.94A 5g5gA-2rhpA:
undetectable
5g5gB-2rhpA:
undetectable		 5g5gA-2rhpA:
15.29
5g5gB-2rhpA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 5 GLY A1090
PRO A1054
THR A1088
THR A1071
 None
None
None
NAG  A   4 (-4.4A)
 1.16A 5h5fA-2rhpA:
undetectable		 5h5fA-2rhpA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 ASP A 995
PRO A 969
GLN A 990
GLY A 997
SER A1034
 None
 1.20A 5hfjB-2rhpA:
undetectable		 5hfjB-2rhpA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 ASP A 995
PRO A 969
GLN A 990
GLY A 997
SER A1034
 None
 1.24A 5hfjG-2rhpA:
undetectable		 5hfjG-2rhpA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 6 ASP A 718
GLY A 699
ASP A1164
ASP A 696
 CA  A  29 ( 2.3A)
None
None
CA  A  28 ( 2.6A)
 1.20A 5hp1A-2rhpA:
undetectable		 5hp1A-2rhpA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		4 / 7 ARG A 960
PHE A 959
LEU A1152
SER A1011
 None
 1.25A 5uxcA-2rhpA:
undetectable		 5uxcA-2rhpA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 ASN A 851
VAL A1039
LEU A1082
GLY A 997
ILE A 998
 None
 1.16A 5vooB-2rhpA:
undetectable		 5vooB-2rhpA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 2rhp THROMBOSPONDIN-2
(Homo
sapiens) 		5 / 12 GLN A 728
GLY A 727
VAL A 980
GLY A 699
ALA A1109
 None
 1.06A 6c2mD-2rhpA:
undetectable		 6c2mD-2rhpA:
7.83