SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ri8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 GLU A1362
TYR A1365
PHE A1414
 NAG  A1700 (-4.7A)
None
None
 0.79A 1eqbB-2ri8A:
undetectable		 1eqbB-2ri8A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 GLU A1362
TYR A1365
PHE A1414
 NAG  A1700 (-4.7A)
None
None
 0.80A 1eqbA-2ri8A:
undetectable		 1eqbA-2ri8A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 GLU A1362
TYR A1365
PHE A1414
 NAG  A1700 (-4.7A)
None
None
 0.79A 1eqbD-2ri8A:
undetectable		 1eqbD-2ri8A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 GLU A1362
TYR A1365
PHE A1414
 NAG  A1700 (-4.7A)
None
None
 0.80A 1eqbC-2ri8A:
undetectable		 1eqbC-2ri8A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 GLU A1472
GLU A1502
ASP A1375
GLU A1409
 GOL  A1901 (-2.7A)
GOL  A1901 (-3.3A)
None
None
 1.18A 1knyA-2ri8A:
undetectable
1knyB-2ri8A:
undetectable		 1knyA-2ri8A:
19.91
1knyB-2ri8A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		5 / 10 GLY A1373
VAL A1410
ALA A1436
ALA A1433
ILE A1437
 None
 1.11A 1likA-2ri8A:
undetectable		 1likA-2ri8A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		5 / 11 GLY A1493
VAL A1420
ILE A1351
GLY A1341
ILE A1274
 None
 0.91A 1n49B-2ri8A:
undetectable		 1n49B-2ri8A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		5 / 11 GLY A1493
VAL A1420
ILE A1351
GLY A1341
ILE A1274
 None
 0.93A 1n49C-2ri8A:
undetectable		 1n49C-2ri8A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 GLU A1472
GLU A1502
ILE A1125
LEU A1330
 GOL  A1901 (-2.7A)
GOL  A1901 (-3.3A)
None
None
 1.50A 1q0yH-2ri8A:
undetectable
1q0yL-2ri8A:
undetectable		 1q0yH-2ri8A:
17.36
1q0yL-2ri8A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 6 LEU A1243
TRP A1262
LEU A1315
PHE A1338
 None
 1.26A 1ru9H-2ri8A:
undetectable
1ru9L-2ri8A:
undetectable		 1ru9H-2ri8A:
17.52
1ru9L-2ri8A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 6 LEU A1243
TRP A1262
LEU A1315
PHE A1338
 None
 1.25A 1rukH-2ri8A:
undetectable
1rukL-2ri8A:
undetectable		 1rukH-2ri8A:
17.52
1rukL-2ri8A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		5 / 10 ALA A1436
GLN A1465
LEU A1469
LEU A1406
SER A1439
 None
 1.41A 2ceoB-2ri8A:
undetectable		 2ceoB-2ri8A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.42A 2v2gA-2ri8A:
undetectable
2v2gB-2ri8A:
undetectable		 2v2gA-2ri8A:
19.08
2v2gB-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.43A 2v2gA-2ri8A:
undetectable
2v2gB-2ri8A:
undetectable		 2v2gA-2ri8A:
19.08
2v2gB-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.43A 2v2gC-2ri8A:
undetectable
2v2gD-2ri8A:
undetectable		 2v2gC-2ri8A:
19.08
2v2gD-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.43A 2v2gC-2ri8A:
undetectable
2v2gD-2ri8A:
undetectable		 2v2gC-2ri8A:
19.08
2v2gD-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.50A 2v32A-2ri8A:
undetectable
2v32B-2ri8A:
undetectable		 2v32A-2ri8A:
19.08
2v32B-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.45A 2v32A-2ri8A:
undetectable
2v32B-2ri8A:
undetectable		 2v32A-2ri8A:
19.08
2v32B-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.41A 2v32C-2ri8A:
undetectable
2v32D-2ri8A:
undetectable		 2v32C-2ri8A:
19.08
2v32D-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.45A 2v32C-2ri8A:
undetectable
2v32D-2ri8A:
undetectable		 2v32C-2ri8A:
19.08
2v32D-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.40A 2v41C-2ri8A:
undetectable
2v41D-2ri8A:
undetectable		 2v41C-2ri8A:
19.08
2v41D-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.42A 2v41C-2ri8A:
undetectable
2v41D-2ri8A:
undetectable		 2v41C-2ri8A:
19.08
2v41D-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.47A 2v41E-2ri8A:
undetectable
2v41F-2ri8A:
undetectable		 2v41E-2ri8A:
19.08
2v41F-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.45A 2v41E-2ri8A:
undetectable
2v41F-2ri8A:
undetectable		 2v41E-2ri8A:
19.08
2v41F-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.40A 2v41G-2ri8A:
undetectable
2v41H-2ri8A:
undetectable		 2v41G-2ri8A:
19.08
2v41H-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 8 THR A1066
PRO A1067
VAL A1068
SER A1069
 None
 0.44A 2v41G-2ri8A:
undetectable
2v41H-2ri8A:
undetectable		 2v41G-2ri8A:
19.08
2v41H-2ri8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 GLY A1336
TYR A1416
SER A1413
 None
 0.76A 2xatA-2ri8A:
undetectable		 2xatA-2ri8A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		5 / 8 MET A1131
GLY A1134
LEU A1155
GLY A1154
ASP A1153
 None
 1.26A 2yfxA-2ri8A:
undetectable		 2yfxA-2ri8A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 TYR A1272
GLU A1409
ASP A1375
 None
 0.84A 3bxoA-2ri8A:
undetectable		 3bxoA-2ri8A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 6 GLU A1466
ASN A1464
SER A1082
PHE A1470
 GOL  A1903 (-2.9A)
None
None
None
 1.37A 3i9jB-2ri8A:
undetectable		 3i9jB-2ri8A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 6 LEU A1162
ALA A1081
ASP A1063
THR A1123
 None
 1.01A 3rozA-2ri8A:
undetectable		 3rozA-2ri8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		5 / 11 ASN A1194
ILE A1248
ASP A1266
ALA A1197
THR A1201
 None
None
None
GOL  A1900 (-3.3A)
None
 1.20A 3rukD-2ri8A:
undetectable		 3rukD-2ri8A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 6 GLU A1466
GLU A1064
ARG A1126
SER A1075
 GOL  A1903 (-2.9A)
None
GOL  A1901 ( 4.0A)
None
 1.37A 4kr3A-2ri8A:
undetectable		 4kr3A-2ri8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 GLU A1271
TYR A1476
GLU A1472
 CA  A1550 ( 4.3A)
None
GOL  A1901 (-2.7A)
 0.76A 4ryaA-2ri8A:
undetectable		 4ryaA-2ri8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 TYR A1055
ALA A1471
SER A1088
ILE A1102
 None
 0.99A 4uymA-2ri8A:
undetectable		 4uymA-2ri8A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 SER A1261
THR A1331
GLY A1264
GLY A1265
 None
None
GOL  A1900 ( 3.9A)
GOL  A1900 (-3.5A)
 0.74A 4yjiA-2ri8A:
undetectable		 4yjiA-2ri8A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 ASN A1366
SER A1367
ARG A1309
 NAG  A1700 (-1.9A)
None
NAG  A1701 (-4.3A)
 0.97A 5b2qA-2ri8A:
0.0		 5b2qA-2ri8A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 7 SER A1088
GLY A1134
TYR A1499
ALA A1129
 None
 0.98A 5e26A-2ri8A:
undetectable
5e26B-2ri8A:
undetectable		 5e26A-2ri8A:
22.80
5e26B-2ri8A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 THR A1193
ALA A1256
ASN A1249
 None
 0.51A 5ersA-2ri8A:
undetectable		 5ersA-2ri8A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		5 / 12 ALA A1295
ASP A1352
PHE A1350
GLY A1354
SER A1337
 None
 1.32A 5hfjG-2ri8A:
undetectable		 5hfjG-2ri8A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		5 / 11 LEU A1155
TYR A1135
GLY A1140
ILE A1152
VAL A1146
 None
 1.22A 5hjiA-2ri8A:
undetectable		 5hjiA-2ri8A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		4 / 5 VAL A1508
ASP A1280
PRO A1281
ALA A1509
 None
 1.05A 5otrA-2ri8A:
undetectable		 5otrA-2ri8A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E
(Penicillium
citrinum) 		3 / 3 PRO A1234
SER A1236
SER A1237
 None
 0.67A 6bpyA-2ri8A:
undetectable		 6bpyA-2ri8A:
22.40