SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 4 GLY A 267
ASP A 310
GLY A 355
THR A 304
 None
 0.96A 1hxbB-2rijA:
undetectable		 1hxbB-2rijA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 9 GLY A 275
SER A 302
ILE A 260
THR A 251
VAL A 256
 CL  A 387 ( 3.8A)
None
None
None
None
 1.36A 2nnhB-2rijA:
undetectable		 2nnhB-2rijA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 ASP A  33
SER A  46
TYR A 141
HIS A 210
 None
 1.20A 2v0gA-2rijA:
undetectable		 2v0gA-2rijA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 4 GLY A 267
ASP A 310
GLY A 355
THR A 304
 None
 0.97A 3k4vC-2rijA:
undetectable		 3k4vC-2rijA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 ILE A  12
PHE A   8
ASP A   7
GLU A   6
 None
 1.05A 3kp6A-2rijA:
undetectable
3kp6B-2rijA:
undetectable		 3kp6A-2rijA:
16.49
3kp6B-2rijA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A 252
VAL A 266
GLY A 249
ALA A 233
GLY A 234
 None
 0.90A 3ku1A-2rijA:
undetectable		 3ku1A-2rijA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A 252
VAL A 266
GLY A 249
ALA A 233
GLY A 234
 None
 0.91A 3ku1C-2rijA:
undetectable		 3ku1C-2rijA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 PHE A  80
SER A 124
GLN A  82
 None
 0.99A 3smtA-2rijA:
undetectable		 3smtA-2rijA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 LEU A 321
PHE A 326
ILE A 306
 None
 0.75A 5dzk1-2rijA:
undetectable
5dzkF-2rijA:
undetectable
5dzkM-2rijA:
undetectable		 5dzk1-2rijA:
18.18
5dzkF-2rijA:
20.31
5dzkM-2rijA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 ILE A 318
ILE A 313
MET A 370
 None
 0.67A 5i9yA-2rijA:
undetectable		 5i9yA-2rijA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2rij PUTATIVE
2,3,4,5-TETRAHYDROPY
RIDINE-2-CARBOXYLATE
N-
SUCCINYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A 359
GLY A 355
PHE A 343
PHE A 341
ASN A 338
 None
 1.45A 6a94A-2rijA:
undetectable		 6a94A-2rijA:
23.60