SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HC4_A_VDXA525_1 (VITAMIN D RECEPTOR)	2rjn	RESPONSE REGULATOR RECEIVER:METAL-DEPEN DENT PHOSPHOHYDROLASE, HD SUBDOMAIN (Neptuniibacter caesariensis)	5 / 12	VAL A 83 SER A 104 VAL A 10 LEU A 30 LEU A 23	None	1.39A	2hc4A-2rjnA: undetectable	2hc4A-2rjnA: 18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	2rjn	RESPONSE REGULATOR RECEIVER:METAL-DEPEN DENT PHOSPHOHYDROLASE, HD SUBDOMAIN (Neptuniibacter caesariensis)	3 / 3	LEU A 41 PRO A 40 LEU A 44	None	0.62A	2po5B-2rjnA: 5.2	2po5B-2rjnA: 17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UXO_B_TACB1211_1 (HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR)	2rjn	RESPONSE REGULATOR RECEIVER:METAL-DEPEN DENT PHOSPHOHYDROLASE, HD SUBDOMAIN (Neptuniibacter caesariensis)	5 / 11	LEU A 124 VAL A 120 LEU A 20 ILE A 80 VAL A 83	None	1.22A	2uxoB-2rjnA: undetectable	2uxoB-2rjnA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UQ6_A_ADNA401_2 (ADENOSINE KINASE, PUTATIVE)	2rjn	RESPONSE REGULATOR RECEIVER:METAL-DEPEN DENT PHOSPHOHYDROLASE, HD SUBDOMAIN (Neptuniibacter caesariensis)	4 / 5	LEU A 41 ALA A 43 MET A 61 PHE A 69	None	1.50A	3uq6A-2rjnA: 5.5	3uq6A-2rjnA: 17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_C_MXMC606_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2rjn	RESPONSE REGULATOR RECEIVER:METAL-DEPEN DENT PHOSPHOHYDROLASE, HD SUBDOMAIN (Neptuniibacter caesariensis)	5 / 12	ILE A 34 VAL A 10 LEU A 54 LEU A 12 VAL A 119	None	1.12A	4m11C-2rjnA: undetectable	4m11C-2rjnA: 14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_D_MXMD606_1 (PROSTAGLANDIN G/H SYNTHASE 2)	2rjn	RESPONSE REGULATOR RECEIVER:METAL-DEPEN DENT PHOSPHOHYDROLASE, HD SUBDOMAIN (Neptuniibacter caesariensis)	5 / 12	ILE A 34 VAL A 10 LEU A 54 LEU A 12 VAL A 119	None	1.10A	4m11D-2rjnA: undetectable	4m11D-2rjnA: 14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NUK_A_Z80A201_1 (BETA-LACTOGLOBULIN)	2rjn	RESPONSE REGULATOR RECEIVER:METAL-DEPEN DENT PHOSPHOHYDROLASE, HD SUBDOMAIN (Neptuniibacter caesariensis)	5 / 10	VAL A 52 ILE A 56 VAL A 120 ALA A 127 GLN A 53	None	1.19A	5nukA-2rjnA: undetectable	5nukA-2rjnA: 21.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HC4_A_VDXA525_1","VITAMIN D RECEPTOR","2rjn","RESPONSE REGULATOR RECEIVER:METAL-DEPENDENT PHOSPHOHYDROLASE, HD SUBDOMAIN","Neptuniibacter caesariensis",5,"VAL A  83;SER A 104;VAL A  10;LEU A  30;LEU A  23","None","1.39A","2hc4A-2rjnA:undetectable","2hc4A-2rjnA:18.81"],["2PO5_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","2rjn","RESPONSE REGULATOR RECEIVER:METAL-DEPENDENT PHOSPHOHYDROLASE, HD SUBDOMAIN","Neptuniibacter caesariensis",3,"LEU A  41;PRO A  40;LEU A  44","None","0.62A","2po5B-2rjnA:5.2","2po5B-2rjnA:17.93"],["2UXO_B_TACB1211_1","HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR","2rjn","RESPONSE REGULATOR RECEIVER:METAL-DEPENDENT PHOSPHOHYDROLASE, HD SUBDOMAIN","Neptuniibacter caesariensis",5,"LEU A 124;VAL A 120;LEU A  20;ILE A  80;VAL A  83","None","1.22A","2uxoB-2rjnA:undetectable","2uxoB-2rjnA:22.73"],["3UQ6_A_ADNA401_2","ADENOSINE KINASE, PUTATIVE","2rjn","RESPONSE REGULATOR RECEIVER:METAL-DEPENDENT PHOSPHOHYDROLASE, HD SUBDOMAIN","Neptuniibacter caesariensis",4,"LEU A  41;ALA A  43;MET A  61;PHE A  69","None","1.50A","3uq6A-2rjnA:5.5","3uq6A-2rjnA:17.58"],["4M11_C_MXMC606_1","PROSTAGLANDIN G\/H SYNTHASE 2","2rjn","RESPONSE REGULATOR RECEIVER:METAL-DEPENDENT PHOSPHOHYDROLASE, HD SUBDOMAIN","Neptuniibacter caesariensis",5,"ILE A  34;VAL A  10;LEU A  54;LEU A  12;VAL A 119","None","1.12A","4m11C-2rjnA:undetectable","4m11C-2rjnA:14.61"],["4M11_D_MXMD606_1","PROSTAGLANDIN G\/H SYNTHASE 2","2rjn","RESPONSE REGULATOR RECEIVER:METAL-DEPENDENT PHOSPHOHYDROLASE, HD SUBDOMAIN","Neptuniibacter caesariensis",5,"ILE A  34;VAL A  10;LEU A  54;LEU A  12;VAL A 119","None","1.10A","4m11D-2rjnA:undetectable","4m11D-2rjnA:14.61"],["5NUK_A_Z80A201_1","BETA-LACTOGLOBULIN","2rjn","RESPONSE REGULATOR RECEIVER:METAL-DEPENDENT PHOSPHOHYDROLASE, HD SUBDOMAIN","Neptuniibacter caesariensis",5,"VAL A  52;ILE A  56;VAL A 120;ALA A 127;GLN A  53","None","1.19A","5nukA-2rjnA:undetectable","5nukA-2rjnA:21.57"]]