SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 2rjz PILO PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLN A 138
ILE A 142
TYR A 141
 None
 0.70A 1vifA-2rjzA:
undetectable		 1vifA-2rjzA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2rjz PILO PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 122
GLY A 124
ILE A 116
GLY A 163
LEU A 167
 None
 1.19A 4n48B-2rjzA:
undetectable		 4n48B-2rjzA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2rjz PILO PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 173
TYR A 141
PRO A 145
ILE A 146
 None
 1.25A 5esgA-2rjzA:
undetectable		 5esgA-2rjzA:
15.96