SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rmr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2rmr PAIRED AMPHIPATHIC
HELIX PROTEIN SIN3A
(Mus
musculus) 		4 / 8 TYR A 129
LEU A 148
TYR A 144
PHE A 147
 None
 1.21A 3po7A-2rmrA:
undetectable		 3po7A-2rmrA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 2rmr PAIRED AMPHIPATHIC
HELIX PROTEIN SIN3A
(Mus
musculus) 		4 / 5 VAL A 164
ARG A 167
MET A 151
GLU A 153
 None
 1.41A 4hojA-2rmrA:
undetectable		 4hojA-2rmrA:
15.66