SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ro9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2ro9 CALMODULIN-2
(Glycine
max) 		5 / 11 PHE A  92
ILE A 100
LEU A 105
LEU A 112
MET A 124
 None
 1.02A 1dtlA-2ro9A:
11.1		 1dtlA-2ro9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2ro9 CALMODULIN-2
(Glycine
max) 		5 / 11 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 124
 None
 0.94A 1dtlA-2ro9A:
11.1		 1dtlA-2ro9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 2ro9 CALMODULIN-2
(Glycine
max) 		5 / 11 LEU A  85
ILE A 136
ILE A 100
VAL A 144
MET A 145
 None
 1.43A 1gx9A-2ro9A:
undetectable		 1gx9A-2ro9A:
19.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2ro9 CALMODULIN-2
(Glycine
max) 		7 / 12 PHE A  92
ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
ILE A 125
 None
 1.31A 1lxfC-2ro9A:
9.2		 1lxfC-2ro9A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2ro9 CALMODULIN-2
(Glycine
max) 		7 / 12 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 124
ILE A 125
MET A 145
 None
 1.21A 1lxfC-2ro9A:
9.2		 1lxfC-2ro9A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2ro9 CALMODULIN-2
(Glycine
max) 		7 / 12 PHE A  92
LEU A 105
MET A 109
MET A 124
ILE A 125
GLU A 127
MET A 145
 None
 1.43A 1lxfC-2ro9A:
9.2		 1lxfC-2ro9A:
39.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2ro9 CALMODULIN-2
(Glycine
max) 		3 / 3 ASP A  95
LYS A  94
ASP A  93
 CA  A 221 (-4.0A)
None
CA  A 221 (-3.5A)
 0.66A 4a7tA-2ro9A:
undetectable		 4a7tA-2ro9A:
20.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2ro9 CALMODULIN-2
(Glycine
max) 		4 / 8 ILE A 100
LEU A 105
MET A 109
ALA A 128
 None
 0.43A 4rjdA-2ro9A:
13.0		 4rjdA-2ro9A:
86.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2ro9 CALMODULIN-2
(Glycine
max) 		4 / 8 PHE A  92
ILE A 100
LEU A 105
ALA A 128
 None
 0.42A 4rjdA-2ro9A:
13.0		 4rjdA-2ro9A:
86.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2ro9 CALMODULIN-2
(Glycine
max) 		4 / 7 LEU A 105
MET A 109
ALA A 128
MET A 145
 None
 0.65A 4rjdB-2ro9A:
12.7		 4rjdB-2ro9A:
86.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2ro9 CALMODULIN-2
(Glycine
max) 		4 / 7 PHE A  92
LEU A 105
MET A 109
ALA A 128
 None
 0.66A 4rjdB-2ro9A:
12.7		 4rjdB-2ro9A:
86.36