SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 2rob CALMODULIN
(Glycine
max) 		5 / 8 ILE A 100
GLU A 127
ALA A 128
VAL A 136
MET A 144
 None
 1.35A 1a29A-2robA:
11.2		 1a29A-2robA:
59.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 2rob CALMODULIN
(Glycine
max) 		5 / 8 ILE A 100
LEU A 105
GLU A 127
ALA A 128
VAL A 136
 None
 1.06A 1a29A-2robA:
11.2		 1a29A-2robA:
59.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 2rob CALMODULIN
(Glycine
max) 		5 / 9 ILE A 100
LEU A 105
GLU A 127
ALA A 128
VAL A 136
 None
 1.05A 1ctrA-2robA:
10.5		 1ctrA-2robA:
59.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2rob CALMODULIN
(Glycine
max) 		5 / 11 ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
 None
 0.85A 1dtlA-2robA:
10.4		 1dtlA-2robA:
23.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2rob CALMODULIN
(Glycine
max) 		7 / 12 LEU A 105
MET A 109
LEU A 112
MET A 124
ILE A 125
GLU A 127
VAL A 136
 None
 1.02A 1lxfC-2robA:
9.1		 1lxfC-2robA:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2rob CALMODULIN
(Glycine
max) 		4 / 5 PHE A  92
LEU A 112
PHE A 141
MET A 145
 None
 1.04A 1wrkB-2robA:
11.3		 1wrkB-2robA:
40.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2rob CALMODULIN
(Glycine
max) 		4 / 7 PHE A  92
LEU A 112
PHE A 141
MET A 145
 None
 1.09A 1wrlA-2robA:
11.3
1wrlB-2robA:
11.1		 1wrlA-2robA:
40.23
1wrlB-2robA:
40.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2rob CALMODULIN
(Glycine
max) 		5 / 6 PHE A  92
VAL A 108
LEU A 112
PHE A 141
MET A 145
 None
 1.00A 1wrlB-2robA:
11.1		 1wrlB-2robA:
40.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2rob CALMODULIN
(Glycine
max) 		4 / 5 PHE A  92
LEU A 112
PHE A 141
MET A 145
 None
 1.11A 1wrlC-2robA:
10.8		 1wrlC-2robA:
40.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 2rob CALMODULIN
(Glycine
max) 		4 / 7 HIS A 107
ASN A 111
LEU A 112
PHE A 141
 None
 1.12A 4awuA-2robA:
undetectable		 4awuA-2robA:
13.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2rob CALMODULIN
(Glycine
max) 		4 / 8 ILE A 100
ALA A 128
VAL A 136
MET A 144
 None
 0.58A 4rjdA-2robA:
11.5		 4rjdA-2robA:
80.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2rob CALMODULIN
(Glycine
max) 		4 / 8 ILE A 100
LEU A 105
ALA A 128
VAL A 136
 None
 0.67A 4rjdA-2robA:
11.5		 4rjdA-2robA:
80.60