SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rq5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 2rq5 PROTEIN JUMONJI
(Mus
musculus) 		4 / 4 LEU A 645
PRO A 644
LEU A 651
ARG A 683
 None
 1.39A 2hrcA-2rq5A:
undetectable		 2hrcA-2rq5A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 2rq5 PROTEIN JUMONJI
(Mus
musculus) 		4 / 6 GLU A 712
LEU A 717
ARG A 716
ARG A 715
 None
 1.25A 5l6eA-2rq5A:
undetectable
5l6eB-2rq5A:
undetectable		 5l6eA-2rq5A:
18.75
5l6eB-2rq5A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2rq5 PROTEIN JUMONJI
(Mus
musculus) 		5 / 12 LEU A 695
ILE A 646
GLY A 647
THR A 687
LEU A 678
 None
 0.88A 5nfjA-2rq5A:
undetectable		 5nfjA-2rq5A:
21.53