SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		3 / 3 ARG A 120
GLU A  91
THR A  95
 None
 0.78A 3v4tA-2rq7A:
undetectable		 3v4tA-2rq7A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 9 LEU A  24
LEU A  31
GLY A  32
VAL A  74
VAL A  69
 None
 1.28A 4c9kB-2rq7A:
undetectable		 4c9kB-2rq7A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 12 ILE A  76
THR A  42
LEU A  31
GLY A  32
VAL A  69
 None
 0.98A 4c9lA-2rq7A:
undetectable		 4c9lA-2rq7A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 10 LEU A  24
LEU A  31
GLY A  32
VAL A  74
VAL A  69
 None
 1.28A 4c9nB-2rq7A:
undetectable		 4c9nB-2rq7A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 12 ILE A  76
THR A  42
LEU A  31
GLY A  32
VAL A  69
 None
 1.00A 4c9oA-2rq7A:
undetectable		 4c9oA-2rq7A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 12 ILE A  76
THR A  42
LEU A  31
GLY A  32
VAL A  69
 None
 0.98A 4c9oB-2rq7A:
undetectable		 4c9oB-2rq7A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 12 VAL A  74
ALA A  67
LEU A  31
THR A  42
GLY A  32
 None
 0.83A 4rzvB-2rq7A:
undetectable		 4rzvB-2rq7A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 12 VAL A  74
ALA A  67
LEU A  31
THR A  42
GLY A  32
 None
 0.83A 5cswA-2rq7A:
undetectable		 5cswA-2rq7A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 12 VAL A  74
ALA A  67
LEU A  31
THR A  42
GLY A  32
 None
 0.80A 5cswB-2rq7A:
undetectable		 5cswB-2rq7A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 12 VAL A  74
ALA A  67
LEU A  31
THR A  42
GLY A  32
 None
 0.83A 5hieB-2rq7A:
undetectable		 5hieB-2rq7A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 12 VAL A  74
ALA A  67
LEU A  31
THR A  42
GLY A  32
 None
 0.81A 5hieD-2rq7A:
undetectable		 5hieD-2rq7A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 9 LEU A  44
PRO A  25
VAL A  48
LEU A  62
ARG A 120
 None
 1.37A 5o96E-2rq7A:
undetectable
5o96F-2rq7A:
undetectable		 5o96E-2rq7A:
20.08
5o96F-2rq7A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)		 2rq7 ATP SYNTHASE EPSILON
CHAIN
(Spinacia
oleracea;
Thermosynechococ
cus
elongatus) 		5 / 10 VAL A  74
GLU A  21
MET A  49
LEU A  31
THR A  42
 None
 1.46A 6d9hR-2rq7A:
undetectable		 6d9hR-2rq7A:
19.08