SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rrb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2rrb CDNA FLJ40872 FIS,
CLONE TUTER2000283,
HIGHLY SIMILAR TO
HOMO SAPIENS
TRANSFORMER-2-BETA
(SFRS10) GENE
(Homo
sapiens) 		4 / 6 THR A 129
LEU A 184
VAL A 147
VAL A 164
 None
 0.74A 2z97A-2rrbA:
undetectable		 2z97A-2rrbA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2rrb CDNA FLJ40872 FIS,
CLONE TUTER2000283,
HIGHLY SIMILAR TO
HOMO SAPIENS
TRANSFORMER-2-BETA
(SFRS10) GENE
(Homo
sapiens) 		4 / 8 THR A 129
LEU A 184
VAL A 147
VAL A 164
 None
 0.71A 2zujA-2rrbA:
undetectable		 2zujA-2rrbA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2rrb CDNA FLJ40872 FIS,
CLONE TUTER2000283,
HIGHLY SIMILAR TO
HOMO SAPIENS
TRANSFORMER-2-BETA
(SFRS10) GENE
(Homo
sapiens) 		4 / 6 PHE A 166
ILE A 144
ARG A 135
VAL A 122
 None
 1.23A 4mk4B-2rrbA:
undetectable		 4mk4B-2rrbA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2rrb CDNA FLJ40872 FIS,
CLONE TUTER2000283,
HIGHLY SIMILAR TO
HOMO SAPIENS
TRANSFORMER-2-BETA
(SFRS10) GENE
(Homo
sapiens) 		4 / 7 VAL A 147
ILE A 149
VAL A 122
ALA A 162
 None
 0.69A 5ospA-2rrbA:
undetectable		 5ospA-2rrbA:
17.16