SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rs5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.80A 1a7yA-2rs52:
undetectable		 1a7yA-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.81A 1a7yB-2rs52:
undetectable		 1a7yB-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 145
PRO 2 149
THR 2 147
 None
 0.77A 1i3wE-2rs52:
undetectable		 1i3wE-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.86A 1i3wE-2rs52:
undetectable		 1i3wE-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.80A 1i3wF-2rs52:
undetectable		 1i3wF-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 145
PRO 2 149
THR 2 147
 None
 0.82A 1i3wG-2rs52:
undetectable		 1i3wG-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.85A 1i3wH-2rs52:
undetectable		 1i3wH-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 145
PRO 2 149
THR 2 147
 None
 0.86A 1mnvD-2rs52:
undetectable		 1mnvD-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 ASN 2  30
ALA 2  28
ASN 2 194
 None
 0.83A 1n4fA-2rs52:
undetectable		 1n4fA-2rs52:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 145
PRO 2 149
THR 2 147
 None
 0.75A 1ovfB-2rs52:
undetectable		 1ovfB-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.81A 1qfiA-2rs52:
undetectable		 1qfiA-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.81A 1qfiB-2rs52:
undetectable		 1qfiB-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.76A 1unjF-2rs52:
undetectable		 1unjF-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 145
PRO 2 149
THR 2 147
 None
 0.84A 1unjL-2rs52:
undetectable		 1unjL-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.85A 1unjL-2rs52:
undetectable		 1unjL-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.84A 1unjR-2rs52:
undetectable		 1unjR-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.83A 1unjX-2rs52:
undetectable		 1unjX-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 147
THR 2 145
PRO 2 149
 None
 0.85A 1unmE-2rs52:
undetectable		 1unmE-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 THR 2 145
PRO 2 149
THR 2 147
 None
 0.87A 1unmF-2rs52:
undetectable		 1unmF-2rs52:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		5 / 12 LEU 2 191
LEU 2 228
SER 2 237
VAL 2 222
TRP 2  78
 None
 1.29A 2pnjB-2rs52:
undetectable		 2pnjB-2rs52:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 HIS 2 130
MET 2 221
MET 2 173
 None
 1.22A 2vj1A-2rs52:
undetectable		 2vj1A-2rs52:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		5 / 12 GLY 2  77
HIS 2 130
LEU 2 220
VAL 2 110
ILE 2 240
 None
 0.97A 3g9eA-2rs52:
undetectable		 3g9eA-2rs52:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		4 / 7 LEU 2 181
ILE 2 201
ILE 2 199
VAL 2 108
 None
 0.71A 4ojbA-2rs52:
undetectable		 4ojbA-2rs52:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)
(Rhinovirus
B) 		3 / 3 ASP 2  57
LEU 2  18
GLY 2  19
 None
 0.48A 4xmfA-2rs52:
undetectable		 4xmfA-2rs52:
21.86