SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rs7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 2rs7 ATP-DEPENDENT RNA
HELICASE A
(Mus
musculus) 		5 / 9 ILE A 219
ILE A 221
LEU A 252
LEU A 248
TYR A 200
 None
 1.48A 3f78A-2rs7A:
undetectable		 3f78A-2rs7A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 2rs7 ATP-DEPENDENT RNA
HELICASE A
(Mus
musculus) 		5 / 9 ILE A 219
ILE A 221
LEU A 252
LEU A 248
TYR A 200
 None
 1.49A 3f78B-2rs7A:
undetectable		 3f78B-2rs7A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 2rs7 ATP-DEPENDENT RNA
HELICASE A
(Mus
musculus) 		3 / 3 ASN A 182
SER A 263
SER A 262
 None
 0.54A 5gsnA-2rs7A:
undetectable		 5gsnA-2rs7A:
14.88