SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2rtt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 1d1vA-2rttA:
0.0
1d1vB-2rttA:
undetectable		 1d1vA-2rttA:
15.21
1d1vB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 1d1vA-2rttA:
0.0
1d1vB-2rttA:
0.0		 1d1vA-2rttA:
15.21
1d1vB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 1d1wA-2rttA:
0.0
1d1wB-2rttA:
0.0		 1d1wA-2rttA:
15.21
1d1wB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 1d1wA-2rttA:
0.0
1d1wB-2rttA:
undetectable		 1d1wA-2rttA:
15.21
1d1wB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 1d1xA-2rttA:
0.0
1d1xB-2rttA:
0.0		 1d1xA-2rttA:
15.21
1d1xB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 1d1xA-2rttA:
0.0
1d1xB-2rttA:
0.0		 1d1xA-2rttA:
15.21
1d1xB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 1dm8A-2rttA:
0.0
1dm8B-2rttA:
0.0		 1dm8A-2rttA:
15.21
1dm8B-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_B_H4BB2600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 1dm8A-2rttA:
0.0
1dm8B-2rttA:
0.0		 1dm8A-2rttA:
15.21
1dm8B-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.40A 1dmiA-2rttA:
0.0
1dmiB-2rttA:
0.0		 1dmiA-2rttA:
15.21
1dmiB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_A_H4BA1600_1
(NITRIC-OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 1fopA-2rttA:
0.0
1fopB-2rttA:
0.0		 1fopA-2rttA:
15.21
1fopB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_B_H4BB2600_1
(NITRIC-OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 1fopA-2rttA:
0.0
1fopB-2rttA:
0.0		 1fopA-2rttA:
15.21
1fopB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 1nseA-2rttA:
0.0
1nseB-2rttA:
undetectable		 1nseA-2rttA:
15.21
1nseB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 1nseA-2rttA:
0.0
1nseB-2rttA:
0.0		 1nseA-2rttA:
15.21
1nseB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 1p6lA-2rttA:
0.0
1p6lB-2rttA:
undetectable		 1p6lA-2rttA:
12.83
1p6lB-2rttA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 1p6lA-2rttA:
0.0
1p6lB-2rttA:
undetectable		 1p6lA-2rttA:
12.83
1p6lB-2rttA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.39A 1p6mA-2rttA:
0.0
1p6mB-2rttA:
0.0		 1p6mA-2rttA:
12.83
1p6mB-2rttA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 1p6mA-2rttA:
0.0
1p6mB-2rttA:
0.0		 1p6mA-2rttA:
12.83
1p6mB-2rttA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.34A 1p6nA-2rttA:
0.0
1p6nB-2rttA:
0.0		 1p6nA-2rttA:
12.83
1p6nB-2rttA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 1p6nA-2rttA:
0.0
1p6nB-2rttA:
0.0		 1p6nA-2rttA:
12.83
1p6nB-2rttA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 1q2oA-2rttA:
0.0
1q2oB-2rttA:
0.0		 1q2oA-2rttA:
15.71
1q2oB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 1q2oA-2rttA:
0.0
1q2oB-2rttA:
0.0		 1q2oA-2rttA:
15.71
1q2oB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.38A 1rs8A-2rttA:
0.0
1rs8B-2rttA:
0.0		 1rs8A-2rttA:
15.71
1rs8B-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 1rs8A-2rttA:
0.0
1rs8B-2rttA:
0.0		 1rs8A-2rttA:
15.71
1rs8B-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 1rs9A-2rttA:
undetectable
1rs9B-2rttA:
0.0		 1rs9A-2rttA:
15.71
1rs9B-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 1rs9A-2rttA:
0.0
1rs9B-2rttA:
0.0		 1rs9A-2rttA:
15.71
1rs9B-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
VAL A  55
 None
 1.25A 1zzrA-2rttA:
undetectable
1zzrB-2rttA:
undetectable		 1zzrA-2rttA:
16.05
1zzrB-2rttA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 1zzsA-2rttA:
0.0
1zzsB-2rttA:
0.0		 1zzsA-2rttA:
15.71
1zzsB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 1zzsA-2rttA:
0.0
1zzsB-2rttA:
0.0		 1zzsA-2rttA:
15.71
1zzsB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 2hx2A-2rttA:
0.0
2hx2B-2rttA:
0.0		 2hx2A-2rttA:
15.71
2hx2B-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.41A 2hx2A-2rttA:
0.0
2hx2B-2rttA:
0.0		 2hx2A-2rttA:
15.71
2hx2B-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 5 ALA A  53
TRP A  35
LEU A  96
ALA A  64
 None
 1.17A 2jstA-2rttA:
undetectable
2jstB-2rttA:
undetectable		 2jstA-2rttA:
15.32
2jstB-2rttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 2nseA-2rttA:
0.0
2nseB-2rttA:
undetectable		 2nseA-2rttA:
15.21
2nseB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2rtt CHIC
(Streptomyces
coelicolor) 		5 / 12 VAL A  47
SER A  80
THR A  23
VAL A  37
ALA A  64
 None
 1.13A 2x2iA-2rttA:
undetectable		 2x2iA-2rttA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2rtt CHIC
(Streptomyces
coelicolor) 		5 / 12 VAL A  47
SER A  80
THR A  23
VAL A  37
ALA A  64
 None
 1.25A 2x2iC-2rttA:
undetectable		 2x2iC-2rttA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 3dqsA-2rttA:
0.0
3dqsB-2rttA:
0.0		 3dqsA-2rttA:
15.71
3dqsB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 3dqsA-2rttA:
0.0
3dqsB-2rttA:
undetectable		 3dqsA-2rttA:
15.71
3dqsB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 3dqtA-2rttA:
0.0
3dqtB-2rttA:
undetectable		 3dqtA-2rttA:
15.71
3dqtB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 3dqtA-2rttA:
undetectable
3dqtB-2rttA:
undetectable		 3dqtA-2rttA:
15.71
3dqtB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.49A 3jwxA-2rttA:
0.0
3jwxB-2rttA:
undetectable		 3jwxA-2rttA:
15.21
3jwxB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.49A 3jwxA-2rttA:
0.0
3jwxB-2rttA:
0.0		 3jwxA-2rttA:
15.21
3jwxB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 3jwyA-2rttA:
0.0
3jwyB-2rttA:
0.0		 3jwyA-2rttA:
15.21
3jwyB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 3jwyA-2rttA:
0.0
3jwyB-2rttA:
0.0		 3jwyA-2rttA:
15.21
3jwyB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 3jwzA-2rttA:
0.0
3jwzB-2rttA:
undetectable		 3jwzA-2rttA:
15.21
3jwzB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.40A 3jwzA-2rttA:
0.0
3jwzB-2rttA:
0.0		 3jwzA-2rttA:
15.21
3jwzB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 VAL A  37
VAL A  55
PHE A  41
GLU A  38
 None
 1.26A 3jx5A-2rttA:
undetectable
3jx5B-2rttA:
undetectable		 3jx5A-2rttA:
15.95
3jx5B-2rttA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.38A 3n5pA-2rttA:
0.0
3n5pB-2rttA:
0.0		 3n5pA-2rttA:
15.21
3n5pB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Q_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 3n5qA-2rttA:
0.0
3n5qB-2rttA:
0.0		 3n5qA-2rttA:
15.21
3n5qB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 3n5rA-2rttA:
0.0
3n5rB-2rttA:
undetectable		 3n5rA-2rttA:
15.21
3n5rB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 3n5rA-2rttA:
0.0
3n5rB-2rttA:
0.0		 3n5rA-2rttA:
15.21
3n5rB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 3n5sA-2rttA:
0.0
3n5sB-2rttA:
0.0		 3n5sA-2rttA:
15.21
3n5sB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 3n5sA-2rttA:
undetectable
3n5sB-2rttA:
undetectable		 3n5sA-2rttA:
15.21
3n5sB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 3n5tA-2rttA:
undetectable
3n5tB-2rttA:
undetectable		 3n5tA-2rttA:
15.21
3n5tB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 3n5tA-2rttA:
0.0
3n5tB-2rttA:
undetectable		 3n5tA-2rttA:
15.21
3n5tB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.32A 3n61A-2rttA:
undetectable
3n61B-2rttA:
undetectable		 3n61A-2rttA:
15.95
3n61B-2rttA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.30A 3n61A-2rttA:
undetectable
3n61B-2rttA:
undetectable		 3n61A-2rttA:
15.95
3n61B-2rttA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 3n6eA-2rttA:
0.0
3n6eB-2rttA:
undetectable		 3n6eA-2rttA:
15.21
3n6eB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 3n6eA-2rttA:
0.0
3n6eB-2rttA:
0.0		 3n6eA-2rttA:
15.21
3n6eB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 3n6fA-2rttA:
0.0
3n6fB-2rttA:
0.0		 3n6fA-2rttA:
15.21
3n6fB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 3n6fA-2rttA:
0.0
3n6fB-2rttA:
0.0		 3n6fA-2rttA:
15.21
3n6fB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 3n6gA-2rttA:
0.0
3n6gB-2rttA:
0.0		 3n6gA-2rttA:
15.21
3n6gB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.40A 3n6gA-2rttA:
0.0
3n6gB-2rttA:
0.0		 3n6gA-2rttA:
15.21
3n6gB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLD_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.38A 3nldA-2rttA:
0.0
3nldB-2rttA:
0.0		 3nldA-2rttA:
15.21
3nldB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.48A 3nleA-2rttA:
0.0
3nleB-2rttA:
undetectable		 3nleA-2rttA:
15.21
3nleB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.48A 3nleA-2rttA:
0.0
3nleB-2rttA:
undetectable		 3nleA-2rttA:
15.21
3nleB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 3nlfA-2rttA:
0.0
3nlfB-2rttA:
0.0		 3nlfA-2rttA:
15.21
3nlfB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 3nlgA-2rttA:
undetectable
3nlgB-2rttA:
undetectable		 3nlgA-2rttA:
15.21
3nlgB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 3nlgA-2rttA:
0.0
3nlgB-2rttA:
0.0		 3nlgA-2rttA:
15.21
3nlgB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 3nlhA-2rttA:
0.0
3nlhB-2rttA:
0.0		 3nlhA-2rttA:
15.21
3nlhB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 3nlhA-2rttA:
0.0
3nlhB-2rttA:
0.0		 3nlhA-2rttA:
15.21
3nlhB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 3nliA-2rttA:
0.0
3nliB-2rttA:
0.0		 3nliA-2rttA:
15.21
3nliB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.48A 3nliA-2rttA:
0.0
3nliB-2rttA:
0.0		 3nliA-2rttA:
15.21
3nliB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
VAL A  55
 None
 1.29A 3nljA-2rttA:
undetectable
3nljB-2rttA:
undetectable		 3nljA-2rttA:
15.95
3nljB-2rttA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 3nluA-2rttA:
0.0
3nluB-2rttA:
0.0		 3nluA-2rttA:
15.21
3nluB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 3nosA-2rttA:
0.0
3nosB-2rttA:
0.0		 3nosA-2rttA:
12.85
3nosB-2rttA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.49A 3nosA-2rttA:
0.0
3nosB-2rttA:
0.0		 3nosA-2rttA:
12.85
3nosB-2rttA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.48A 3pnhA-2rttA:
0.0
3pnhB-2rttA:
undetectable		 3pnhA-2rttA:
15.71
3pnhB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.48A 3pnhA-2rttA:
0.0
3pnhB-2rttA:
0.0		 3pnhA-2rttA:
15.71
3pnhB-2rttA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.47A 3rqoA-2rttA:
0.0
3rqoB-2rttA:
0.0		 3rqoA-2rttA:
15.25
3rqoB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 3rqpA-2rttA:
0.0
3rqpB-2rttA:
0.0		 3rqpA-2rttA:
15.25
3rqpB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 4c3aA-2rttA:
0.0
4c3aB-2rttA:
0.0		 4c3aA-2rttA:
15.25
4c3aB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 4c3aA-2rttA:
0.0
4c3aB-2rttA:
0.0		 4c3aA-2rttA:
15.25
4c3aB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 4carA-2rttA:
0.0
4carB-2rttA:
undetectable		 4carA-2rttA:
15.25
4carB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 4carA-2rttA:
0.0
4carB-2rttA:
undetectable		 4carA-2rttA:
15.25
4carB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 4cftA-2rttA:
0.0
4cftB-2rttA:
undetectable		 4cftA-2rttA:
15.25
4cftB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 4cftA-2rttA:
0.0
4cftB-2rttA:
0.0		 4cftA-2rttA:
15.25
4cftB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 4ctyA-2rttA:
0.0
4ctyB-2rttA:
undetectable		 4ctyA-2rttA:
15.25
4ctyB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.41A 4ctyA-2rttA:
0.0
4ctyB-2rttA:
0.0		 4ctyA-2rttA:
15.25
4ctyB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.37A 4ctzA-2rttA:
0.0
4ctzB-2rttA:
0.0		 4ctzA-2rttA:
15.25
4ctzB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.41A 4ctzA-2rttA:
0.0
4ctzB-2rttA:
undetectable		 4ctzA-2rttA:
15.25
4ctzB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.48A 4cu0A-2rttA:
0.0
4cu0B-2rttA:
0.0		 4cu0A-2rttA:
15.25
4cu0B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 4cu0A-2rttA:
0.0
4cu0B-2rttA:
0.0		 4cu0A-2rttA:
15.25
4cu0B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 4cu1A-2rttA:
0.0
4cu1B-2rttA:
0.0		 4cu1A-2rttA:
15.25
4cu1B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 4cu1A-2rttA:
0.0
4cu1B-2rttA:
0.0		 4cu1A-2rttA:
15.25
4cu1B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.48A 4cwvA-2rttA:
0.0
4cwvB-2rttA:
0.0		 4cwvA-2rttA:
15.25
4cwvB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.48A 4cwvA-2rttA:
0.0
4cwvB-2rttA:
0.0		 4cwvA-2rttA:
15.25
4cwvB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.49A 4cwwA-2rttA:
0.0
4cwwB-2rttA:
undetectable		 4cwwA-2rttA:
15.25
4cwwB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 4cwwA-2rttA:
0.0
4cwwB-2rttA:
0.0		 4cwwA-2rttA:
15.25
4cwwB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.47A 4cwxA-2rttA:
undetectable
4cwxB-2rttA:
undetectable		 4cwxA-2rttA:
15.25
4cwxB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 4cwyA-2rttA:
undetectable
4cwyB-2rttA:
undetectable		 4cwyA-2rttA:
15.25
4cwyB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.49A 4cwyA-2rttA:
undetectable
4cwyB-2rttA:
undetectable		 4cwyA-2rttA:
15.25
4cwyB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 4cwzA-2rttA:
0.0
4cwzB-2rttA:
0.0		 4cwzA-2rttA:
15.25
4cwzB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 4cwzA-2rttA:
0.0
4cwzB-2rttA:
0.0		 4cwzA-2rttA:
15.25
4cwzB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 4cx0A-2rttA:
0.0
4cx0B-2rttA:
undetectable		 4cx0A-2rttA:
15.25
4cx0B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.37A 4cx0A-2rttA:
0.0
4cx0B-2rttA:
0.0		 4cx0A-2rttA:
15.25
4cx0B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_A_H4BA1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 4d1oA-2rttA:
0.0
4d1oB-2rttA:
0.0		 4d1oA-2rttA:
15.38
4d1oB-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.41A 4d1oA-2rttA:
0.0
4d1oB-2rttA:
0.0		 4d1oA-2rttA:
15.38
4d1oB-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.40A 4d1pA-2rttA:
0.0
4d1pB-2rttA:
0.0		 4d1pA-2rttA:
15.38
4d1pB-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 4d33A-2rttA:
0.0
4d33B-2rttA:
0.0		 4d33A-2rttA:
15.25
4d33B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.48A 4d33A-2rttA:
0.0
4d33B-2rttA:
0.0		 4d33A-2rttA:
15.25
4d33B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 4d34A-2rttA:
0.0
4d34B-2rttA:
0.0		 4d34A-2rttA:
15.25
4d34B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 4d34A-2rttA:
0.0
4d34B-2rttA:
0.0		 4d34A-2rttA:
15.25
4d34B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.36A 4d35A-2rttA:
0.0
4d35B-2rttA:
0.0		 4d35A-2rttA:
15.25
4d35B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 4d36A-2rttA:
0.0
4d36B-2rttA:
0.0		 4d36A-2rttA:
15.25
4d36B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 4d36A-2rttA:
0.0
4d36B-2rttA:
0.0		 4d36A-2rttA:
15.25
4d36B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 4d37A-2rttA:
0.0
4d37B-2rttA:
0.0		 4d37A-2rttA:
15.25
4d37B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.49A 4d37A-2rttA:
0.0
4d37B-2rttA:
0.0		 4d37A-2rttA:
15.25
4d37B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 4d38A-2rttA:
0.0
4d38B-2rttA:
0.0		 4d38A-2rttA:
15.25
4d38B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.47A 4d38A-2rttA:
0.0
4d38B-2rttA:
undetectable		 4d38A-2rttA:
15.25
4d38B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 4d39A-2rttA:
0.0
4d39B-2rttA:
0.0		 4d39A-2rttA:
15.25
4d39B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 4d39A-2rttA:
0.0
4d39B-2rttA:
0.0		 4d39A-2rttA:
15.25
4d39B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 4d3aA-2rttA:
0.0
4d3aB-2rttA:
0.0		 4d3aA-2rttA:
15.25
4d3aB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.47A 4d3aA-2rttA:
0.0
4d3aB-2rttA:
undetectable		 4d3aA-2rttA:
15.25
4d3aB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 4imxA-2rttA:
0.0
4imxB-2rttA:
0.0		 4imxA-2rttA:
15.30
4imxB-2rttA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.41A 4imxA-2rttA:
0.0
4imxB-2rttA:
0.0		 4imxA-2rttA:
15.30
4imxB-2rttA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 4jskA-2rttA:
0.0
4jskB-2rttA:
0.0		 4jskA-2rttA:
15.25
4jskB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.39A 4jslA-2rttA:
0.0
4jslB-2rttA:
0.0		 4jslA-2rttA:
15.25
4jslB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.39A 4jslA-2rttA:
0.0
4jslB-2rttA:
0.0		 4jslA-2rttA:
15.25
4jslB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 4jsmA-2rttA:
0.0
4jsmB-2rttA:
0.0		 4jsmA-2rttA:
15.25
4jsmB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 4jsmA-2rttA:
0.0
4jsmB-2rttA:
undetectable		 4jsmA-2rttA:
15.25
4jsmB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 4k5hA-2rttA:
0.0
4k5hB-2rttA:
0.0		 4k5hA-2rttA:
15.25
4k5hB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 4k5hA-2rttA:
0.0
4k5hB-2rttA:
0.0		 4k5hA-2rttA:
15.25
4k5hB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 4k5iA-2rttA:
0.0
4k5iB-2rttA:
0.0		 4k5iA-2rttA:
15.25
4k5iB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 4k5iA-2rttA:
0.0
4k5iB-2rttA:
0.0		 4k5iA-2rttA:
15.25
4k5iB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 4k5jA-2rttA:
0.0
4k5jB-2rttA:
undetectable		 4k5jA-2rttA:
15.25
4k5jB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 4k5jA-2rttA:
undetectable
4k5jB-2rttA:
undetectable		 4k5jA-2rttA:
15.25
4k5jB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 4k5kA-2rttA:
0.0
4k5kB-2rttA:
0.0		 4k5kA-2rttA:
15.25
4k5kB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 4k5kA-2rttA:
0.0
4k5kB-2rttA:
0.0		 4k5kA-2rttA:
15.25
4k5kB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 4kcpA-2rttA:
0.0
4kcpB-2rttA:
0.0		 4kcpA-2rttA:
15.25
4kcpB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 4kcpA-2rttA:
0.0
4kcpB-2rttA:
0.0		 4kcpA-2rttA:
15.25
4kcpB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 4kcqA-2rttA:
0.0
4kcqB-2rttA:
0.0		 4kcqA-2rttA:
15.25
4kcqB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 4kcqA-2rttA:
0.0
4kcqB-2rttA:
0.0		 4kcqA-2rttA:
15.25
4kcqB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 4kcrA-2rttA:
0.0
4kcrB-2rttA:
undetectable		 4kcrA-2rttA:
15.25
4kcrB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 4kcrA-2rttA:
0.0
4kcrB-2rttA:
undetectable		 4kcrA-2rttA:
15.25
4kcrB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 4kcsA-2rttA:
0.0
4kcsB-2rttA:
0.0		 4kcsA-2rttA:
15.25
4kcsB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 4kcsA-2rttA:
0.0
4kcsB-2rttA:
0.0		 4kcsA-2rttA:
15.25
4kcsB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 4luwA-2rttA:
0.0
4luwB-2rttA:
0.0		 4luwA-2rttA:
15.54
4luwB-2rttA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.38A 4luwA-2rttA:
0.0
4luwB-2rttA:
0.0		 4luwA-2rttA:
15.54
4luwB-2rttA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 THR A 104
ALA A   6
THR A   5
ALA A   4
 None
 1.01A 4qw0K-2rttA:
undetectable		 4qw0K-2rttA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 THR A 104
ALA A   6
THR A   5
ALA A   4
 None
 1.01A 4qw0Y-2rttA:
undetectable		 4qw0Y-2rttA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 4uh7A-2rttA:
undetectable
4uh7B-2rttA:
0.0		 4uh7A-2rttA:
15.25
4uh7B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.39A 4uh7A-2rttA:
undetectable
4uh7B-2rttA:
0.0		 4uh7A-2rttA:
15.25
4uh7B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 4uh8A-2rttA:
0.0
4uh8B-2rttA:
0.0		 4uh8A-2rttA:
15.25
4uh8B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 4uh8A-2rttA:
0.0
4uh8B-2rttA:
0.0		 4uh8A-2rttA:
15.25
4uh8B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 4uh9A-2rttA:
undetectable
4uh9B-2rttA:
undetectable		 4uh9A-2rttA:
15.25
4uh9B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 4uh9A-2rttA:
undetectable
4uh9B-2rttA:
undetectable		 4uh9A-2rttA:
15.25
4uh9B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.39A 4uhaA-2rttA:
0.0
4uhaB-2rttA:
0.0		 4uhaA-2rttA:
15.25
4uhaB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.37A 4uhaA-2rttA:
0.0
4uhaB-2rttA:
undetectable		 4uhaA-2rttA:
15.25
4uhaB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 4upqA-2rttA:
0.0
4upqB-2rttA:
undetectable		 4upqA-2rttA:
15.25
4upqB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 4upqA-2rttA:
0.0
4upqB-2rttA:
undetectable		 4upqA-2rttA:
15.25
4upqB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 4uprA-2rttA:
0.0
4uprB-2rttA:
0.0		 4uprA-2rttA:
15.25
4uprB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 4uprA-2rttA:
0.0
4uprB-2rttA:
0.0		 4uprA-2rttA:
15.25
4uprB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 4upsA-2rttA:
0.0
4upsB-2rttA:
0.0		 4upsA-2rttA:
15.25
4upsB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 4upsA-2rttA:
0.0
4upsB-2rttA:
0.0		 4upsA-2rttA:
15.25
4upsB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 4uptA-2rttA:
0.0
4uptB-2rttA:
0.0		 4uptA-2rttA:
15.25
4uptB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 4uptA-2rttA:
0.0
4uptB-2rttA:
undetectable		 4uptA-2rttA:
15.25
4uptB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.31A 5adeA-2rttA:
undetectable
5adeB-2rttA:
undetectable		 5adeA-2rttA:
15.95
5adeB-2rttA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
VAL A  55
 None
 1.29A 5adeA-2rttA:
undetectable
5adeB-2rttA:
undetectable		 5adeA-2rttA:
15.95
5adeB-2rttA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 5adjA-2rttA:
0.0
5adjB-2rttA:
0.0		 5adjA-2rttA:
15.25
5adjB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 5adjA-2rttA:
0.0
5adjB-2rttA:
0.0		 5adjA-2rttA:
15.25
5adjB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 5adkA-2rttA:
0.0
5adkB-2rttA:
0.0		 5adkA-2rttA:
15.25
5adkB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 5adkA-2rttA:
0.0
5adkB-2rttA:
0.0		 5adkA-2rttA:
15.25
5adkB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 5adlA-2rttA:
0.0
5adlB-2rttA:
0.0		 5adlA-2rttA:
15.25
5adlB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 5adlA-2rttA:
undetectable
5adlB-2rttA:
undetectable		 5adlA-2rttA:
15.25
5adlB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 5admA-2rttA:
0.0
5admB-2rttA:
0.0		 5admA-2rttA:
15.25
5admB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 5admA-2rttA:
undetectable
5admB-2rttA:
undetectable		 5admA-2rttA:
15.25
5admB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 5adnA-2rttA:
0.0
5adnB-2rttA:
undetectable		 5adnA-2rttA:
15.25
5adnB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.41A 5adnA-2rttA:
0.0
5adnB-2rttA:
0.0		 5adnA-2rttA:
15.25
5adnB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.38A 5fj2A-2rttA:
0.0
5fj2B-2rttA:
0.0		 5fj2A-2rttA:
15.25
5fj2B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 5fj2A-2rttA:
0.0
5fj2B-2rttA:
undetectable		 5fj2A-2rttA:
15.25
5fj2B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 5fj3A-2rttA:
0.0
5fj3B-2rttA:
0.0		 5fj3A-2rttA:
15.25
5fj3B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.39A 5fj3A-2rttA:
undetectable
5fj3B-2rttA:
undetectable		 5fj3A-2rttA:
15.25
5fj3B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 5fvyA-2rttA:
0.0
5fvyB-2rttA:
0.0		 5fvyA-2rttA:
15.25
5fvyB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 5fvyA-2rttA:
0.0
5fvyB-2rttA:
0.0		 5fvyA-2rttA:
15.25
5fvyB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 5fvzA-2rttA:
0.0
5fvzB-2rttA:
0.0		 5fvzA-2rttA:
15.25
5fvzB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.40A 5fvzA-2rttA:
0.0
5fvzB-2rttA:
undetectable		 5fvzA-2rttA:
15.25
5fvzB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.48A 5uo8A-2rttA:
0.0
5uo8B-2rttA:
0.0		 5uo8A-2rttA:
15.38
5uo8B-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 5uo8C-2rttA:
0.0
5uo8D-2rttA:
0.0		 5uo8C-2rttA:
15.38
5uo8D-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.40A 5uo8C-2rttA:
0.0
5uo8D-2rttA:
0.0		 5uo8C-2rttA:
15.38
5uo8D-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 5uo9A-2rttA:
0.0
5uo9B-2rttA:
0.0		 5uo9A-2rttA:
15.38
5uo9B-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.44A 5uo9A-2rttA:
undetectable
5uo9B-2rttA:
undetectable		 5uo9A-2rttA:
15.38
5uo9B-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 5uo9C-2rttA:
0.0
5uo9D-2rttA:
0.0		 5uo9C-2rttA:
15.38
5uo9D-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.34A 5uo9C-2rttA:
undetectable
5uo9D-2rttA:
undetectable		 5uo9C-2rttA:
15.38
5uo9D-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 5uodA-2rttA:
0.0
5uodB-2rttA:
0.0		 5uodA-2rttA:
15.25
5uodB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.39A 5uodA-2rttA:
0.0
5uodB-2rttA:
0.0		 5uodA-2rttA:
15.25
5uodB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.45A 5vv6A-2rttA:
0.0
5vv6B-2rttA:
0.0		 5vv6A-2rttA:
15.25
5vv6B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.47A 5vv6A-2rttA:
0.0
5vv6B-2rttA:
undetectable		 5vv6A-2rttA:
15.25
5vv6B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 5vv7A-2rttA:
0.0
5vv7B-2rttA:
0.0		 5vv7A-2rttA:
15.25
5vv7B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 5vv7A-2rttA:
undetectable
5vv7B-2rttA:
undetectable		 5vv7A-2rttA:
15.25
5vv7B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.47A 5vv8A-2rttA:
0.0
5vv8B-2rttA:
undetectable		 5vv8A-2rttA:
15.25
5vv8B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 5vv8A-2rttA:
0.0
5vv8B-2rttA:
0.0		 5vv8A-2rttA:
15.25
5vv8B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 5vv9A-2rttA:
undetectable
5vv9B-2rttA:
undetectable		 5vv9A-2rttA:
15.25
5vv9B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 5vv9A-2rttA:
0.0
5vv9B-2rttA:
0.0		 5vv9A-2rttA:
15.25
5vv9B-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.47A 5vvaA-2rttA:
0.0
5vvaB-2rttA:
0.0		 5vvaA-2rttA:
15.25
5vvaB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.46A 5vvbA-2rttA:
0.0
5vvbB-2rttA:
0.0		 5vvbA-2rttA:
15.38
5vvbB-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.49A 5vvbC-2rttA:
0.0
5vvbD-2rttA:
0.0		 5vvbC-2rttA:
15.38
5vvbD-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 5vvcA-2rttA:
undetectable
5vvcB-2rttA:
0.0		 5vvcA-2rttA:
15.38
5vvcB-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 5vvcC-2rttA:
0.0
5vvcD-2rttA:
0.0		 5vvcC-2rttA:
15.38
5vvcD-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.36A 5vvcC-2rttA:
undetectable
5vvcD-2rttA:
undetectable		 5vvcC-2rttA:
15.38
5vvcD-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 5vvdA-2rttA:
undetectable
5vvdB-2rttA:
undetectable		 5vvdA-2rttA:
15.38
5vvdB-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 5vvdC-2rttA:
0.0
5vvdD-2rttA:
0.0		 5vvdC-2rttA:
15.38
5vvdD-2rttA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.48A 5vvgA-2rttA:
0.0
5vvgB-2rttA:
0.0		 5vvgA-2rttA:
15.25
5vvgB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.47A 5vvgA-2rttA:
0.0
5vvgB-2rttA:
0.0		 5vvgA-2rttA:
15.25
5vvgB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.48A 5vvnA-2rttA:
0.0
5vvnB-2rttA:
0.0		 5vvnA-2rttA:
15.25
5vvnB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 5vvnA-2rttA:
undetectable
5vvnB-2rttA:
undetectable		 5vvnA-2rttA:
15.25
5vvnB-2rttA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.43A 6av6A-2rttA:
undetectable
6av6B-2rttA:
undetectable		 6av6A-2rttA:
22.61
6av6B-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.40A 6av6A-2rttA:
undetectable
6av6B-2rttA:
undetectable		 6av6A-2rttA:
22.61
6av6B-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.38A 6av6C-2rttA:
undetectable
6av6D-2rttA:
0.0		 6av6C-2rttA:
22.61
6av6D-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.37A 6av6C-2rttA:
undetectable
6av6D-2rttA:
undetectable		 6av6C-2rttA:
22.61
6av6D-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.46A 6av7A-2rttA:
undetectable
6av7B-2rttA:
undetectable		 6av7A-2rttA:
22.61
6av7B-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 6av7A-2rttA:
undetectable
6av7B-2rttA:
0.0		 6av7A-2rttA:
22.61
6av7B-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.40A 6av7C-2rttA:
0.0
6av7D-2rttA:
0.0		 6av7C-2rttA:
22.61
6av7D-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.38A 6av7C-2rttA:
0.0
6av7D-2rttA:
0.0		 6av7C-2rttA:
22.61
6av7D-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.41A 6cieA-2rttA:
0.0
6cieB-2rttA:
0.0		 6cieA-2rttA:
22.61
6cieB-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 7 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.45A 6cieA-2rttA:
undetectable
6cieB-2rttA:
undetectable		 6cieA-2rttA:
22.61
6cieB-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.42A 6cieC-2rttA:
0.0
6cieD-2rttA:
0.0		 6cieC-2rttA:
22.61
6cieD-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.39A 6cieC-2rttA:
0.0
6cieD-2rttA:
0.0		 6cieC-2rttA:
22.61
6cieD-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.43A 6cifA-2rttA:
0.0
6cifB-2rttA:
0.0		 6cifA-2rttA:
22.61
6cifB-2rttA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.39A 8nseA-2rttA:
0.0
8nseB-2rttA:
0.0		 8nseA-2rttA:
15.21
8nseB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 8nseA-2rttA:
0.0
8nseB-2rttA:
0.0		 8nseA-2rttA:
15.21
8nseB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 VAL A  37
TRP A  22
PHE A  41
GLU A  38
 None
 1.44A 9nseA-2rttA:
0.0
9nseB-2rttA:
0.0		 9nseA-2rttA:
15.21
9nseB-2rttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 2rtt CHIC
(Streptomyces
coelicolor) 		4 / 6 PHE A  41
GLU A  38
VAL A  37
TRP A  22
 None
 1.42A 9nseA-2rttA:
0.0
9nseB-2rttA:
0.0		 9nseA-2rttA:
15.21
9nseB-2rttA:
15.21