SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2snv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 2snv SINDBIS VIRUS COAT
PROTEIN
(Sindbis
virus) 		3 / 3 TRP A 247
TYR A 162
LEU A 231
 None
 1.06A 1kxhA-2snvA:
undetectable		 1kxhA-2snvA:
14.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5G4B_A_PZEA1268_1
(CAPSID PROTEIN)		 2snv SINDBIS VIRUS COAT
PROTEIN
(Sindbis
virus) 		4 / 5 MET A 132
GLU A 133
TYR A 180
TRP A 247
 None
 0.30A 5g4bA-2snvA:
27.5		 5g4bA-2snvA:
75.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_0
(REGULATORY PROTEIN
TETR)		 2snv SINDBIS VIRUS COAT
PROTEIN
(Sindbis
virus) 		5 / 12 MET A 137
LEU A 231
TRP A 247
VAL A 227
PHE A 203
 None
 1.47A 5vlmC-2snvA:
undetectable		 5vlmC-2snvA:
19.61