SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2taa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		3 / 3 LEU A 114
SER A 105
ASN A 197
 None
 0.84A 1bx4A-2taaA:
undetectable		 1bx4A-2taaA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		4 / 8 SER A 409
LEU A 462
TYR A 427
VAL A 444
 None
 0.84A 1fduB-2taaA:
undetectable		 1fduB-2taaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		5 / 8 LEU A 361
ALA A 311
ILE A 308
GLY A 457
PHE A 262
 None
 1.26A 1sv9A-2taaA:
undetectable		 1sv9A-2taaA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		5 / 12 TRP A  42
ALA A 102
TYR A 198
LEU A 103
VAL A  65
 None
 1.29A 1vpoH-2taaA:
undetectable
1vpoL-2taaA:
undetectable		 1vpoH-2taaA:
18.60
1vpoL-2taaA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		4 / 7 GLY A 202
PRO A   3
ASP A   5
TYR A 113
 None
 0.89A 2aouB-2taaA:
undetectable		 2aouB-2taaA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		5 / 10 LEU A 361
ALA A 311
ILE A 308
GLY A 457
PHE A 262
 None
 1.26A 2b17A-2taaA:
undetectable		 2b17A-2taaA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		4 / 5 LEU A 462
ALA A 394
ILE A 407
SER A 409
 None
 1.14A 2othA-2taaA:
undetectable		 2othA-2taaA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		4 / 5 ILE A  62
TYR A  94
ARG A  18
GLY A  81
 None
 1.29A 3b9mA-2taaA:
undetectable		 3b9mA-2taaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		3 / 3 GLY A 470
ASP A 476
SER A 478
 None
 0.60A 3brfA-2taaA:
undetectable		 3brfA-2taaA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		3 / 3 TYR A 352
TYR A  12
ILE A  52
 None
 0.82A 3eteA-2taaA:
undetectable
3eteB-2taaA:
undetectable		 3eteA-2taaA:
22.75
3eteB-2taaA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		4 / 7 LEU A 194
VAL A 249
ILE A 205
ARG A   7
 None
 1.31A 3ik3A-2taaA:
undetectable		 3ik3A-2taaA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		4 / 8 TYR A 252
VAL A 293
TYR A 256
VAL A 314
 None
 1.05A 4aftD-2taaA:
undetectable
4aftE-2taaA:
undetectable		 4aftD-2taaA:
19.09
4aftE-2taaA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		4 / 8 VAL A 293
TYR A 256
VAL A 314
ILE A 254
 None
 1.16A 4aftD-2taaA:
undetectable
4aftE-2taaA:
undetectable		 4aftD-2taaA:
19.09
4aftE-2taaA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		3 / 3 ASP A 117
LEU A 250
GLY A 229
 None
 0.50A 4xmfA-2taaA:
undetectable		 4xmfA-2taaA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		5 / 12 TRP A  61
HIS A 296
ILE A 228
ASN A 295
LEU A 232
 None
 1.31A 4yvpB-2taaA:
7.3		 4yvpB-2taaA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		4 / 8 GLN A  84
GLY A  81
ASP A  77
ASP A  17
 None
 1.00A 5vlmH-2taaA:
undetectable		 5vlmH-2taaA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 2taa TAKA-AMYLASE A
(Aspergillus
oryzae) 		5 / 12 LYS A 209
HIS A 210
TYR A 256
HIS A 296
ASP A 297
 None
 1.32A 6ag0C-2taaA:
22.9		 6ag0C-2taaA:
9.85