SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2trc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2trc PHOSDUCIN
(Rattus
norvegicus) 		4 / 8 ILE P 136
VAL P 165
TYR P 115
CYH P 168
 None
 1.24A 2xz5A-2trcP:
undetectable
2xz5C-2trcP:
undetectable		 2xz5A-2trcP:
19.69
2xz5C-2trcP:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2trc PHOSDUCIN
(Rattus
norvegicus) 		4 / 8 ILE P 136
VAL P 165
TYR P 115
CYH P 168
 None
 1.25A 2xz5C-2trcP:
undetectable
2xz5D-2trcP:
undetectable		 2xz5C-2trcP:
19.69
2xz5D-2trcP:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 2trc PHOSDUCIN
(Rattus
norvegicus) 		4 / 6 SER P 203
GLY P 178
ASP P 179
ARG P 180
 None
 0.82A 5cdpA-2trcP:
undetectable
5cdpB-2trcP:
undetectable		 5cdpA-2trcP:
16.81
5cdpB-2trcP:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 2trc PHOSDUCIN
(Rattus
norvegicus) 		5 / 12 VAL P 137
PHE P 167
ASN P 222
LEU P 158
VAL P 165
 None
 0.87A 5uvmB-2trcP:
undetectable		 5uvmB-2trcP:
19.11