SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PCP_C_1PCC212_1
(IMMUNOGLOBULIN)		 2uud NQ10-1.12 ANTI-PHOX
ANTIBODY
(Mus
musculus) 		5 / 10 HIS K  27
TYR K  32
PHE K  89
GLY K  91
TYR K  96
 None
 0.47A 2pcpC-2uudK:
22.4
2pcpD-2uudK:
14.7		 2pcpC-2uudK:
95.58
2pcpD-2uudK:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2uud NQ10-1.12 ANTI-PHOX
ANTIBODY
(Mus
musculus) 		5 / 7 VAL K  78
ILE K  75
ALA K  19
VAL K  13
GLY K  16
 None
 1.41A 2xrzB-2uudK:
undetectable		 2xrzB-2uudK:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2uud NQ10-1.12 ANTI-PHOX
ANTIBODY
(Mus
musculus) 		4 / 5 TYR H  90
LEU H  20
LEU H  82
ARG H  66
 None
 1.35A 4em2A-2uudH:
undetectable		 4em2A-2uudH:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 2uud NQ10-1.12 ANTI-PHOX
ANTIBODY
(Mus
musculus) 		4 / 5 TYR H  90
LEU H  80
LEU H  82
ARG H  66
 None
 1.26A 4em2A-2uudH:
undetectable		 4em2A-2uudH:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 2uud NQ10-1.12 ANTI-PHOX
ANTIBODY
(Mus
musculus) 		4 / 5 THR H  82
GLY H  16
VAL H  12
PRO H  14
 None
 1.17A 4grkA-2uudH:
undetectable		 4grkA-2uudH:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 2uud NQ10-1.12 ANTI-PHOX
ANTIBODY
(Mus
musculus) 		4 / 4 LEU K  15
VAL K  78
GLU K  79
ARG K  61
 None
 1.31A 4ww7A-2uudK:
0.0		 4ww7A-2uudK:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2uud NQ10-1.12 ANTI-PHOX
ANTIBODY
(Mus
musculus) 		4 / 5 TYR K  87
TYR K  86
GLY K 101
GLY K 100
 None
 1.13A 5x7pA-2uudK:
2.0		 5x7pA-2uudK:
6.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 2uud NQ10-1.12 ANTI-PHOX
ANTIBODY
(Mus
musculus) 		3 / 3 TYR H  59
GLY H  65
THR H  68
 None
 0.18A 6cjkB-2uudH:
20.1		 6cjkB-2uudH:
57.48