SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 8 LEU A  51
THR A  96
VAL A  95
ALA A  40
 None
 0.92A 1fiqC-2uunA:
undetectable		 1fiqC-2uunA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		5 / 12 ALA B 137
GLY B 132
GLY B 130
SER B  53
LEU B  59
 None
 0.94A 1ya4A-2uunB:
undetectable		 1ya4A-2uunB:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 6 PHE B 164
THR B  94
VAL B 142
VAL B  51
 None
None
BLA  B 255 (-4.5A)
None
 1.08A 2feuA-2uunB:
undetectable		 2feuA-2uunB:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		3 / 3 LEU B 113
TYR B 117
GLY B 121
 CYC  B 184 (-3.9A)
None
None
 0.60A 2ocuA-2uunB:
undetectable		 2ocuA-2uunB:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 7 LEU B  90
VAL B  93
THR B  94
VAL B 142
 None
None
None
BLA  B 255 (-4.5A)
 0.99A 2qblA-2uunB:
undetectable		 2qblA-2uunB:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 7 PHE B 164
THR B  94
VAL B 142
VAL B  51
 None
None
BLA  B 255 (-4.5A)
None
 1.05A 2zwtA-2uunB:
undetectable		 2zwtA-2uunB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 8 LEU A  51
THR A  96
VAL A  95
ALA A  40
 None
 1.00A 3ax9A-2uunA:
undetectable		 3ax9A-2uunA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 4 LEU B 105
ARG B 114
LEU B 113
ALA B 169
 None
None
CYC  B 184 (-3.9A)
None
 1.20A 3b9mA-2uunB:
2.4		 3b9mA-2uunB:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		5 / 10 ILE A 115
SER A 162
ASN A 159
TYR A 156
ILE A 112
 None
 1.28A 3u6tA-2uunA:
undetectable		 3u6tA-2uunA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 8 LEU A  51
THR A  96
VAL A  95
ALA A  40
 None
 0.88A 3uniB-2uunA:
undetectable		 3uniB-2uunA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 5 ILE A 115
ASN A 159
TYR A 156
ILE A 112
 None
 1.06A 4jtpA-2uunA:
undetectable		 4jtpA-2uunA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		4 / 6 VAL B  97
VAL B  41
ILE B  44
LEU B 139
 None
 0.97A 4l1wB-2uunB:
undetectable		 4l1wB-2uunB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		5 / 11 ALA B 167
ALA B 169
VAL B  93
GLY B 130
GLY B 132
 None
 0.89A 5lf7K-2uunB:
undetectable
5lf7L-2uunB:
undetectable		 5lf7K-2uunB:
25.36
5lf7L-2uunB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		5 / 11 ALA B 169
VAL B  93
GLY B 130
GLY B 132
ASP B 165
 None
 0.86A 5lf7K-2uunB:
undetectable
5lf7L-2uunB:
undetectable		 5lf7K-2uunB:
25.36
5lf7L-2uunB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		5 / 11 ALA B 167
ALA B 169
VAL B  93
GLY B 130
GLY B 132
 None
 0.90A 5lf7Y-2uunB:
undetectable
5lf7Z-2uunB:
undetectable		 5lf7Y-2uunB:
25.36
5lf7Z-2uunB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2uun C-PHYCOCYANIN
(Leptolyngbya
sp.) 		5 / 11 ALA B 169
VAL B  93
GLY B 130
GLY B 132
ASP B 165
 None
 0.88A 5lf7Y-2uunB:
undetectable
5lf7Z-2uunB:
undetectable		 5lf7Y-2uunB:
25.36
5lf7Z-2uunB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 2uun C-PHYCOCYANIN
C-PHYCOCYANIN
(Leptolyngbya
sp.;
Leptolyngbya
sp.) 		4 / 7 SER A 152
GLY A 102
ALA A 101
VAL B  19
 None
 0.81A 6dwnB-2uunA:
undetectable		 6dwnB-2uunA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 2uun C-PHYCOCYANIN
C-PHYCOCYANIN
(Leptolyngbya
sp.;
Leptolyngbya
sp.) 		5 / 11 GLY B 100
LEU A   5
ALA A  27
ALA B  34
PHE A  31
 None
 1.16A 6qgbE-2uunB:
undetectable		 6qgbE-2uunB:
14.24