SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 8 LEU A 212
PHE A  94
PHE A 210
LEU A 197
PHE A  40
 None
 1.49A 2eilP-2uurA:
undetectable
2eilW-2uurA:
undetectable		 2eilP-2uurA:
17.41
2eilW-2uurA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 10 ILE A 123
ILE A 121
PHE A 172
PRO A 224
LEU A 149
 None
 1.32A 3elzB-2uurA:
undetectable		 3elzB-2uurA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 6 LEU A 212
PHE A  94
PHE A 210
LEU A 197
PHE A  40
 None
 1.48A 3wg7P-2uurA:
undetectable
3wg7W-2uurA:
undetectable		 3wg7P-2uurA:
17.41
3wg7W-2uurA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA301_1
(CHITOSANASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		4 / 4 ASP A 138
GLY A 187
PRO A 188
GLN A 118
 None
 1.36A 4oltA-2uurA:
0.0		 4oltA-2uurA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 ILE A  74
ILE A 121
ASN A 106
PHE A  72
LEU A  66
 None
 1.16A 5fa8A-2uurA:
undetectable		 5fa8A-2uurA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 LEU A 197
THR A  92
GLY A 198
PHE A 210
LEU A 212
 None
 1.42A 5jo9A-2uurA:
undetectable		 5jo9A-2uurA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 LEU A 197
THR A  92
GLY A 198
VAL A 208
LEU A 212
 None
 1.42A 5jo9A-2uurA:
undetectable		 5jo9A-2uurA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 121
PHE A 172
VAL A 173
TYR A  88
ILE A 217
 None
 0.87A 5n0sA-2uurA:
undetectable		 5n0sA-2uurA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 121
PHE A 172
VAL A 173
TYR A  88
ILE A 217
 None
 0.89A 5n0sB-2uurA:
undetectable		 5n0sB-2uurA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 121
PHE A 172
VAL A 173
TYR A  88
ILE A 217
 None
 0.86A 5n0tA-2uurA:
undetectable		 5n0tA-2uurA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 121
PHE A 172
VAL A 173
TYR A  88
ILE A 217
 None
 0.87A 5n0tB-2uurA:
undetectable		 5n0tB-2uurA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 121
PHE A 172
VAL A 173
TYR A  88
ILE A 217
 None
 0.86A 5n0wB-2uurA:
undetectable		 5n0wB-2uurA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 121
PHE A 172
VAL A 173
TYR A  88
ILE A 217
 None
 0.86A 5n0xA-2uurA:
undetectable		 5n0xA-2uurA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 12 ILE A 121
PHE A 172
VAL A 173
TYR A  88
ILE A 217
 None
 0.87A 5n4iA-2uurA:
undetectable		 5n4iA-2uurA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2uur COLLAGEN ALPHA-1(IX)
CHAIN
(Homo
sapiens) 		5 / 9 LEU A 152
SER A 150
PHE A 153
LEU A 101
ASN A 104
 None
 1.49A 6ftpA-2uurA:
undetectable
6ftpB-2uurA:
undetectable		 6ftpA-2uurA:
17.24
6ftpB-2uurA:
10.29