SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uux'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2uux TRYPTASE INHIBITOR
(Rhipicephalus
appendiculatus) 		4 / 7 ARG A  44
GLY A  61
SER A  64
GLU A  68
 None
 0.77A 2c8aB-2uuxA:
undetectable		 2c8aB-2uuxA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2uux TRYPTASE INHIBITOR
(Rhipicephalus
appendiculatus) 		4 / 7 ARG A  44
GLY A  61
SER A  64
GLU A  68
 None
 0.82A 2c8aD-2uuxA:
undetectable		 2c8aD-2uuxA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2uux TRYPTASE INHIBITOR
(Rhipicephalus
appendiculatus) 		4 / 5 TYR A  46
TYR A  45
GLY A  62
GLY A  61
 None
 1.05A 5x7pA-2uuxA:
undetectable		 5x7pA-2uuxA:
3.55