SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A 126
THR A  76
VAL A  73
 None
 0.74A 1hxbA-2uvdA:
undetectable		 1hxbA-2uvdA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A  60
VAL A  92
THR A 112
 None
 0.73A 2nmzA-2uvdA:
undetectable		 2nmzA-2uvdA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A  60
VAL A  92
THR A 112
 None
 0.72A 2nnkA-2uvdA:
undetectable		 2nnkA-2uvdA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A 126
THR A  76
VAL A  73
 None
 0.79A 2qakA-2uvdA:
undetectable		 2qakA-2uvdA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 12 ILE A  20
ALA A  19
GLY A  15
ILE A 218
GLY A  11
 None
 0.81A 2qe6A-2uvdA:
6.6		 2qe6A-2uvdA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 12 ILE A  20
ALA A  19
GLY A  15
ILE A 218
GLY A  11
 None
 0.83A 2qe6B-2uvdA:
5.7		 2qe6B-2uvdA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 12 ILE A  22
LEU A  24
ASN A  89
THR A 189
VAL A   9
 None
 1.04A 3dcjA-2uvdA:
5.4
3dcjB-2uvdA:
5.7		 3dcjA-2uvdA:
26.39
3dcjB-2uvdA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A  60
VAL A  92
THR A 112
 None
 0.70A 3k4vA-2uvdA:
undetectable		 3k4vA-2uvdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A  60
VAL A  92
THR A 112
 None
 0.74A 3k4vD-2uvdA:
undetectable		 3k4vD-2uvdA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		4 / 8 ALA A 215
ALA A 219
THR A 223
LEU A  24
 None
 0.93A 3khmA-2uvdA:
undetectable		 3khmA-2uvdA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		4 / 8 ALA A 215
ALA A 219
THR A 223
LEU A  24
 None
 0.89A 3l4dA-2uvdA:
undetectable		 3l4dA-2uvdA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 10 GLY A  91
ALA A  90
ASN A  34
GLY A  17
ILE A  16
 None
 0.95A 3lzvA-2uvdA:
undetectable		 3lzvA-2uvdA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A  60
VAL A  92
THR A 112
 None
 0.66A 3ndtA-2uvdA:
undetectable		 3ndtA-2uvdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A  60
VAL A  92
THR A 112
 None
 0.77A 3nduD-2uvdA:
undetectable		 3nduD-2uvdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A  60
VAL A  92
THR A 112
 None
 0.68A 3pwrA-2uvdA:
undetectable		 3pwrA-2uvdA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		4 / 8 GLY A  91
ALA A  90
GLY A  17
ILE A  16
 None
 0.70A 3so9A-2uvdA:
undetectable		 3so9A-2uvdA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 12 GLY A  81
ASP A  84
ILE A  49
ALA A  29
ALA A  25
 None
 0.96A 3sudC-2uvdA:
undetectable		 3sudC-2uvdA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 12 GLY A  81
ASP A  84
ILE A  49
ALA A  29
ALA A  25
 None
 1.02A 3sueA-2uvdA:
undetectable		 3sueA-2uvdA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 12 GLY A  81
ASP A  84
ILE A  49
ALA A  29
ALA A  25
 None
 0.99A 3sufD-2uvdA:
undetectable		 3sufD-2uvdA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		3 / 3 ARG A  60
VAL A  92
THR A 112
 None
 0.70A 3tl9A-2uvdA:
undetectable		 3tl9A-2uvdA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		4 / 5 SER A 141
ILE A  16
TYR A 154
GLY A 185
 None
 1.00A 3uboB-2uvdA:
6.9		 3uboB-2uvdA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		4 / 6 ILE A 207
LEU A 204
MET A 191
THR A 189
 None
 1.09A 3wg7A-2uvdA:
undetectable
3wg7J-2uvdA:
undetectable		 3wg7A-2uvdA:
18.73
3wg7J-2uvdA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		4 / 8 LEU A 204
ILE A 207
GLY A 185
ILE A 187
 None
 0.90A 3wxoA-2uvdA:
undetectable		 3wxoA-2uvdA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 11 GLN A  82
PHE A  80
GLY A  81
ALA A  25
GLY A  28
 None
 1.22A 4a6nA-2uvdA:
6.6		 4a6nA-2uvdA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		5 / 11 ILE A  20
ILE A  16
GLY A  15
VAL A 240
GLY A 213
 None
 1.06A 4ac9B-2uvdA:
6.9
4ac9C-2uvdA:
6.5		 4ac9B-2uvdA:
21.35
4ac9C-2uvdA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2uvd 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Bacillus
anthracis) 		4 / 6 ILE A 207
LEU A 204
MET A 191
THR A 189
 None
 0.97A 6nmfN-2uvdA:
undetectable
6nmfW-2uvdA:
undetectable		 6nmfN-2uvdA:
18.73
6nmfW-2uvdA:
12.93