SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uwi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 2uwi CRME PROTEIN
(Vaccinia
virus) 		3 / 3 LYS A 124
ARG A  87
VAL A  88
 None
 0.83A 4x3uA-2uwiA:
undetectable
4x3uB-2uwiA:
undetectable		 4x3uA-2uwiA:
17.83
4x3uB-2uwiA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 2uwi CRME PROTEIN
(Vaccinia
virus) 		4 / 6 ASN A 117
ALA A 113
VAL A 119
ASP A 115
 None
 1.20A 5umd2-2uwiA:
undetectable
5umdF-2uwiA:
undetectable		 5umd2-2uwiA:
19.01
5umdF-2uwiA:
15.97