SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ux0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 2ux0 CALCIUM-CALMODULIN
DEPENDENT PROTEIN
KINASE (CAM KINASE)
II GAMMA
(Homo
sapiens) 		4 / 5 ARG A 506
ALA A 476
ASP A 474
GLY A 472
 None
 1.08A 1e7cA-2ux0A:
undetectable		 1e7cA-2ux0A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2ux0 CALCIUM-CALMODULIN
DEPENDENT PROTEIN
KINASE (CAM KINASE)
II GAMMA
(Homo
sapiens) 		4 / 7 TYR A 516
THR A 461
THR A 484
SER A 498
 None
 1.03A 1tv8A-2ux0A:
undetectable		 1tv8A-2ux0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2ux0 CALCIUM-CALMODULIN
DEPENDENT PROTEIN
KINASE (CAM KINASE)
II GAMMA
(Homo
sapiens) 		4 / 8 TYR A 516
THR A 461
THR A 484
SER A 498
 None
 1.05A 2fb2A-2ux0A:
undetectable		 2fb2A-2ux0A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2ux0 CALCIUM-CALMODULIN
DEPENDENT PROTEIN
KINASE (CAM KINASE)
II GAMMA
(Homo
sapiens) 		4 / 7 TYR A 516
THR A 461
THR A 484
SER A 498
 None
 1.07A 2fb2B-2ux0A:
undetectable		 2fb2B-2ux0A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 2ux0 CALCIUM-CALMODULIN
DEPENDENT PROTEIN
KINASE (CAM KINASE)
II GAMMA
(Homo
sapiens) 		5 / 12 TYR A 418
GLU A 404
ILE A 399
ILE A 463
GLU A 500
 None
 1.49A 4a99A-2ux0A:
undetectable
4a99C-2ux0A:
undetectable		 4a99A-2ux0A:
19.02
4a99C-2ux0A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 2ux0 CALCIUM-CALMODULIN
DEPENDENT PROTEIN
KINASE (CAM KINASE)
II GAMMA
(Homo
sapiens) 		4 / 7 HIS A 444
TYR A 516
ASN A 411
ARG A 502
 GLY  A1521 (-3.9A)
None
None
None
 1.14A 4o7gA-2ux0A:
undetectable
4o7gB-2ux0A:
undetectable		 4o7gA-2ux0A:
21.65
4o7gB-2ux0A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 2ux0 CALCIUM-CALMODULIN
DEPENDENT PROTEIN
KINASE (CAM KINASE)
II GAMMA
(Homo
sapiens) 		4 / 7 PHE A 448
HIS A 444
TYR A 516
ARG A 502
 None
GLY  A1521 (-3.9A)
None
None
 1.34A 4o7gA-2ux0A:
undetectable
4o7gB-2ux0A:
undetectable		 4o7gA-2ux0A:
21.65
4o7gB-2ux0A:
21.65