SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ux7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 4 HIS A  40
CYH A  78
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.39A 1oe1A-2ux7A:
undetectable		 1oe1A-2ux7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		5 / 5 HIS A  40
CYH A  78
PRO A  80
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
None
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.71A 1oe2A-2ux7A:
5.0		 1oe2A-2ux7A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 5 HIS A  40
PRO A  80
HIS A  81
MET A  16
 CU  A1123 (-3.1A)
None
CU  A1123 (-3.6A)
None
 1.49A 1oe2A-2ux7A:
5.0		 1oe2A-2ux7A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 4 HIS A  40
CYH A  78
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.40A 1oe3A-2ux7A:
undetectable		 1oe3A-2ux7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 4 HIS A  40
CYH A  78
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.53A 2fqdA-2ux7A:
undetectable		 2fqdA-2ux7A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 4 HIS A  40
CYH A  78
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.49A 2fqeA-2ux7A:
undetectable		 2fqeA-2ux7A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 4 HIS A  40
CYH A  78
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.48A 2fqfA-2ux7A:
undetectable		 2fqfA-2ux7A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 4 HIS A  40
CYH A  78
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.46A 2fqgA-2ux7A:
undetectable		 2fqgA-2ux7A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 4 HIS A  40
CYH A  78
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.40A 2xxgA-2ux7A:
4.9		 2xxgA-2ux7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		5 / 5 HIS A  40
CYH A  78
PRO A  80
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
None
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.76A 2xxgC-2ux7A:
4.7		 2xxgC-2ux7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 4 HIS A  40
CYH A  78
HIS A  81
MET A  84
 CU  A1123 (-3.1A)
CU  A1123 (-2.1A)
CU  A1123 (-3.6A)
CU  A1123 (-2.3A)
 0.45A 4ef3A-2ux7A:
undetectable		 4ef3A-2ux7A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 8 VAL A  87
LEU A 120
LEU A 117
ASN A  96
 None
 0.91A 4lzrA-2ux7A:
undetectable		 4lzrA-2ux7A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		5 / 12 VAL A  25
ALA A  26
PHE A  33
PHE A  68
GLY A  28
 None
 1.25A 4mm4A-2ux7A:
undetectable		 4mm4A-2ux7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		5 / 12 VAL A  25
ALA A  26
PHE A  33
PHE A  68
GLY A  28
 None
 1.22A 4mm4B-2ux7A:
undetectable		 4mm4B-2ux7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 5 GLN A  89
VAL A  88
PRO A  94
THR A  44
 None
 1.06A 6cduA-2ux7A:
undetectable
6cduB-2ux7A:
undetectable		 6cduA-2ux7A:
16.92
6cduB-2ux7A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2ux7 PSEUDOAZURIN
(Achromobacter
cycloclastes) 		4 / 5 GLN A  89
VAL A  88
PRO A  94
THR A  44
 None
 1.10A 6cduI-2ux7A:
undetectable
6cduJ-2ux7A:
undetectable		 6cduI-2ux7A:
16.92
6cduJ-2ux7A:
16.92