SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uyd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 10 SER X  91
LEU X 155
ILE X  16
SER X 114
SER X   4
 None
 1.26A 3ijxB-2uydX:
undetectable
3ijxD-2uydX:
undetectable		 3ijxB-2uydX:
20.07
3ijxD-2uydX:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 9 PHE X  94
PHE X 115
PHE X  11
GLY X  12
PHE X 166
 None
 1.29A 3ko0A-2uydX:
0.7
3ko0C-2uydX:
undetectable		 3ko0A-2uydX:
16.13
3ko0C-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		4 / 8 GLY X 138
PHE X  11
PHE X 166
PHE X 115
 None
 1.08A 3ko0D-2uydX:
0.9
3ko0E-2uydX:
0.9		 3ko0D-2uydX:
16.13
3ko0E-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 7 PHE X  11
GLY X  12
PHE X 166
PHE X  94
PHE X 115
 None
 1.21A 3ko0D-2uydX:
undetectable
3ko0E-2uydX:
undetectable		 3ko0D-2uydX:
16.13
3ko0E-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		4 / 5 PHE X  11
PHE X 166
PHE X  94
PHE X 115
 None
 1.36A 3ko0F-2uydX:
0.6
3ko0G-2uydX:
0.7		 3ko0F-2uydX:
16.13
3ko0G-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		4 / 5 PHE X  94
PHE X 115
PHE X  11
PHE X 166
 None
 1.41A 3ko0F-2uydX:
0.6
3ko0G-2uydX:
0.7		 3ko0F-2uydX:
16.13
3ko0G-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		4 / 7 GLY X 138
PHE X  11
PHE X 166
PHE X 115
 None
 1.09A 3ko0L-2uydX:
0.6
3ko0N-2uydX:
undetectable		 3ko0L-2uydX:
16.13
3ko0N-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 10 PHE X  11
GLY X  12
PHE X 166
PHE X  94
PHE X 115
 None
 1.24A 3ko0L-2uydX:
0.9
3ko0N-2uydX:
0.9		 3ko0L-2uydX:
16.13
3ko0N-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 8 PHE X  11
GLY X  12
PHE X 166
PHE X  94
PHE X 115
 None
 1.28A 3ko0O-2uydX:
undetectable
3ko0Q-2uydX:
0.7		 3ko0O-2uydX:
16.13
3ko0Q-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 10 PHE X  94
PHE X 115
PHE X  11
GLY X  12
PHE X 166
 None
 1.24A 3ko0R-2uydX:
0.7
3ko0T-2uydX:
0.8		 3ko0R-2uydX:
16.13
3ko0T-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		4 / 7 PHE X 115
GLY X 138
PHE X  11
PHE X 166
 None
 1.10A 3ko0R-2uydX:
0.6
3ko0T-2uydX:
0.8		 3ko0R-2uydX:
16.13
3ko0T-2uydX:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		3 / 3 VAL X 169
SER X 164
LEU X 155
 None
 0.72A 3n8xA-2uydX:
undetectable		 3n8xA-2uydX:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 12 TYR X  86
ALA X 125
GLY X 127
LEU X 123
SER X 122
 None
 1.12A 3pfgA-2uydX:
2.1		 3pfgA-2uydX:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 12 GLY X 101
GLY X  43
ALA X  56
PHE X  67
ALA X  69
 None
 1.10A 3sudA-2uydX:
undetectable		 3sudA-2uydX:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		4 / 7 GLY X 153
ILE X 154
VAL X 135
VAL X 131
 ZN  X 208 (-4.3A)
None
None
None
 0.74A 3ufnB-2uydX:
undetectable		 3ufnB-2uydX:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		4 / 5 TYR X 158
THR X 144
LEU X  20
THR X 165
 None
 1.43A 4mbsB-2uydX:
undetectable		 4mbsB-2uydX:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		6 / 12 LEU X 151
THR X 149
ALA X 146
ILE X 154
GLY X 153
LEU X 139
 None
None
None
None
ZN  X 208 (-4.3A)
None
 1.46A 5nfjA-2uydX:
undetectable		 5nfjA-2uydX:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		6 / 12 LEU X 151
THR X 149
ALA X 146
ILE X 154
LEU X 147
LEU X 139
 None
 1.35A 5nfjA-2uydX:
undetectable		 5nfjA-2uydX:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		5 / 12 LEU X 118
LEU X  89
GLY X  70
VAL X  68
LEU X 147
 None
 1.20A 5uc1A-2uydX:
undetectable		 5uc1A-2uydX:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2uyd HEMOPHORE HASA
(Serratia
marcescens) 		4 / 8 MET X 140
GLY X 130
SER X 122
VAL X 135
 HEM  X 200 (-3.6A)
None
None
None
 1.10A 6giqL-2uydX:
undetectable
6giqP-2uydX:
undetectable
6giqT-2uydX:
undetectable		 6giqL-2uydX:
18.91
6giqP-2uydX:
24.03
6giqT-2uydX:
16.30