SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uyk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		4 / 7 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.26A 1oniA-2uykA:
22.0
1oniB-2uykA:
22.3		 1oniA-2uykA:
39.01
1oniB-2uykA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		4 / 6 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.23A 1oniB-2uykA:
22.3
1oniC-2uykA:
22.3		 1oniB-2uykA:
39.01
1oniC-2uykA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		4 / 6 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.44A 1oniA-2uykA:
22.0
1oniC-2uykA:
22.3		 1oniA-2uykA:
39.01
1oniC-2uykA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		4 / 7 ILE A  14
TYR A  17
ILE A  33
GLU A 120
 None
 0.53A 1oniD-2uykA:
22.2
1oniF-2uykA:
22.3		 1oniD-2uykA:
39.01
1oniF-2uykA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		4 / 7 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.48A 1oniD-2uykA:
22.2
1oniE-2uykA:
22.3		 1oniD-2uykA:
39.01
1oniE-2uykA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		4 / 7 TYR A  17
ILE A  33
PRO A 114
GLU A 120
 None
 0.23A 1oniG-2uykA:
22.3
1oniI-2uykA:
22.2		 1oniG-2uykA:
39.01
1oniI-2uykA:
39.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		4 / 7 ALA A  50
SER A  53
ILE A 121
ILE A  78
 None
 0.87A 1yc5A-2uykA:
undetectable		 1yc5A-2uykA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		3 / 3 ARG A  51
GLN A  93
GLU A  97
 None
 0.80A 4tvtA-2uykA:
undetectable		 4tvtA-2uykA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		3 / 3 GLU A  89
TYR A  91
ARG A 105
 None
 0.76A 5uunA-2uykA:
undetectable		 5uunA-2uykA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2uyk PROTEIN TDCF
(Escherichia
coli) 		3 / 3 GLU A  89
TYR A  91
ARG A 105
 None
 0.80A 5uunB-2uykA:
undetectable		 5uunB-2uykA:
18.97