SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2uzp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2uzp PROTEIN KINASE C
GAMMA TYPE
(Homo
sapiens) 		4 / 8 THR A 218
THR A 212
VAL A 244
VAL A 196
 None
 0.80A 1t86A-2uzpA:
undetectable		 1t86A-2uzpA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2uzp PROTEIN KINASE C
GAMMA TYPE
(Homo
sapiens) 		5 / 12 LEU A 240
LEU A 163
THR A 212
ILE A 201
LEU A 200
 None
 1.07A 2jn3A-2uzpA:
undetectable		 2jn3A-2uzpA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 2uzp PROTEIN KINASE C
GAMMA TYPE
(Homo
sapiens) 		3 / 3 GLN A 210
THR A 208
LEU A 266
 None
 0.63A 3ondA-2uzpA:
undetectable		 3ondA-2uzpA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 2uzp PROTEIN KINASE C
GAMMA TYPE
(Homo
sapiens) 		3 / 3 GLN A 210
THR A 208
LEU A 266
 None
 0.61A 3ondB-2uzpA:
undetectable		 3ondB-2uzpA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2uzp PROTEIN KINASE C
GAMMA TYPE
(Homo
sapiens) 		5 / 12 ASN A 206
THR A 208
LEU A 200
GLU A 284
ARG A 238
 None
 1.47A 4ejwA-2uzpA:
undetectable		 4ejwA-2uzpA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 2uzp PROTEIN KINASE C
GAMMA TYPE
(Homo
sapiens) 		5 / 9 VAL A 196
LEU A 200
LEU A 163
SER A 260
ILE A 165
 None
 1.27A 4ubsA-2uzpA:
undetectable		 4ubsA-2uzpA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2uzp PROTEIN KINASE C
GAMMA TYPE
(Homo
sapiens) 		3 / 3 THR A 218
THR A 212
LEU A 161
 None
 0.63A 5m66D-2uzpA:
undetectable		 5m66D-2uzpA:
17.00