SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 10 LEU A 286
VAL A 290
ILE A 292
LEU A 315
VAL A 320
 None
 1.20A 1cqpA-2v0jA:
undetectable
1cqpB-2v0jA:
undetectable		 1cqpA-2v0jA:
16.89
1cqpB-2v0jA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		6 / 9 LEU A 201
GLY A 171
VAL A 149
ILE A 142
GLY A 140
ILE A 202
 None
 1.40A 1hpvA-2v0jA:
undetectable		 1hpvA-2v0jA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1866_0
(FPRA)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 4 ARG A 141
LEU A 133
ASN A 135
VAL A 168
 None
 1.50A 1lqtA-2v0jA:
2.8		 1lqtA-2v0jA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1875_0
(FPRA)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 4 ARG A 141
LEU A 133
ASN A 135
VAL A 168
 None
 1.49A 1lqtB-2v0jA:
2.2		 1lqtB-2v0jA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1423_0
(FPRA)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 4 ARG A 141
LEU A 133
ASN A 135
VAL A 168
 None
 1.50A 1lquA-2v0jA:
2.7		 1lquA-2v0jA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1432_0
(FPRA)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 4 ARG A 141
LEU A 133
ASN A 135
VAL A 168
 None
 1.49A 1lquB-2v0jA:
1.8		 1lquB-2v0jA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 7 PHE A 260
VAL A 284
VAL A 272
ILE A 274
 None
 0.95A 1p7rA-2v0jA:
undetectable		 1p7rA-2v0jA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 7 SER A  21
MET A  19
GLY A  14
ILE A  10
 None
None
H2U  A1453 ( 3.4A)
None
 1.09A 2bdmA-2v0jA:
undetectable		 2bdmA-2v0jA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 12 LEU A 332
GLY A 345
VAL A 367
ILE A 378
ILE A 350
 None
 0.86A 2f8gB-2v0jA:
undetectable		 2f8gB-2v0jA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 12 VAL A 301
LEU A 298
ILE A 309
ILE A 326
ALA A 324
 None
 0.99A 2gj5A-2v0jA:
undetectable		 2gj5A-2v0jA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 9 PHE A 347
GLU A 349
VAL A 367
GLY A 381
ILE A 383
 None
 1.16A 2w98A-2v0jA:
undetectable		 2w98A-2v0jA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 10 ILE A 109
LEU A  11
VAL A   9
VAL A  86
LEU A 198
 None
H2U  A1453 (-4.0A)
None
None
None
 0.89A 3gwxA-2v0jA:
undetectable		 3gwxA-2v0jA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		6 / 12 LEU A 201
GLY A 171
VAL A 149
ILE A 142
GLY A 140
ILE A 202
 None
 1.32A 3jw2B-2v0jA:
undetectable		 3jw2B-2v0jA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 12 GLY A  16
GLY A  14
LEU A  23
SER A  21
MET A  19
 SO4  A1462 (-3.4A)
H2U  A1453 ( 3.4A)
None
None
None
 1.25A 3sxjA-2v0jA:
undetectable		 3sxjA-2v0jA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 12 GLY A  16
GLY A  14
LEU A  23
SER A  21
MET A  19
 SO4  A1462 (-3.4A)
H2U  A1453 ( 3.4A)
None
None
None
 1.26A 3sxjB-2v0jA:
undetectable		 3sxjB-2v0jA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		6 / 12 LEU A 201
GLY A 171
VAL A 149
ILE A 142
GLY A 140
ILE A 202
 None
 1.32A 3tkwB-2v0jA:
undetectable		 3tkwB-2v0jA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 5 ASP A 200
VAL A 187
GLY A 188
TYR A 197
 None
 1.40A 3w9tA-2v0jA:
undetectable		 3w9tA-2v0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 5 ASP A 200
VAL A 187
GLY A 188
TYR A 197
 None
 1.39A 3w9tB-2v0jA:
undetectable		 3w9tB-2v0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 5 ASP A 200
VAL A 187
GLY A 188
TYR A 197
 None
 1.40A 3w9tC-2v0jA:
undetectable		 3w9tC-2v0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 5 ASP A 200
VAL A 187
GLY A 188
TYR A 197
 None
 1.41A 3w9tD-2v0jA:
undetectable		 3w9tD-2v0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 5 ASP A 200
VAL A 187
GLY A 188
TYR A 197
 None
 1.41A 3w9tE-2v0jA:
undetectable		 3w9tE-2v0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 5 ASP A 200
VAL A 187
GLY A 188
TYR A 197
 None
 1.40A 3w9tF-2v0jA:
undetectable		 3w9tF-2v0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 5 ASP A 200
VAL A 187
GLY A 188
TYR A 197
 None
 1.40A 3w9tG-2v0jA:
undetectable		 3w9tG-2v0jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 12 GLY A 321
ALA A 340
ILE A 319
VAL A 307
ILE A 309
 None
 0.99A 4ax8A-2v0jA:
undetectable		 4ax8A-2v0jA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		6 / 12 GLY A 321
ALA A 340
ILE A 319
ILE A 303
VAL A 307
ILE A 309
 None
 1.36A 4azvA-2v0jA:
undetectable		 4azvA-2v0jA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 8 ILE A 397
LEU A 409
ILE A 350
GLY A 381
 None
 0.90A 4hb6A-2v0jA:
undetectable		 4hb6A-2v0jA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 10 ALA A 419
VAL A 403
GLY A 422
ILE A 438
VAL A 431
 None
None
PG4  A1456 ( 3.7A)
PG4  A1456 ( 4.4A)
None
 1.03A 4j5jB-2v0jA:
undetectable		 4j5jB-2v0jA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 5 TYR A 139
GLY A 225
ASP A 105
VAL A 100
 None
None
H2U  A1453 (-2.7A)
None
 1.15A 4nkvD-2v0jA:
undetectable		 4nkvD-2v0jA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 10 ASP A 208
LEU A 184
ALA A 185
LEU A 198
ALA A  83
 None
 1.12A 4zbrA-2v0jA:
undetectable		 4zbrA-2v0jA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 7 VAL A 172
THR A 170
LEU A 114
THR A 113
 None
 1.01A 5e4dA-2v0jA:
undetectable
5e4dB-2v0jA:
undetectable		 5e4dA-2v0jA:
18.52
5e4dB-2v0jA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		3 / 3 ASN A 305
VAL A 252
HIS A 268
 None
 0.84A 6a5yD-2v0jA:
undetectable		 6a5yD-2v0jA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		4 / 6 LEU A 129
ALA A 217
LEU A 102
THR A  42
 None
 0.72A 6f88B-2v0jA:
undetectable		 6f88B-2v0jA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 2v0j BIFUNCTIONAL PROTEIN
GLMU
(Haemophilus
influenzae) 		5 / 12 LEU A  27
GLU A  69
VAL A  36
PRO A  34
GLY A 282
 None
 1.42A 6mn8A-2v0jA:
undetectable		 6mn8A-2v0jA:
21.63