SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2v0o FCH DOMAIN ONLY
PROTEIN 2
(Homo
sapiens) 		3 / 3 THR A  32
GLU A 206
HIS A  27
 None
 0.87A 1xwfA-2v0oA:
undetectable		 1xwfA-2v0oA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2v0o FCH DOMAIN ONLY
PROTEIN 2
(Homo
sapiens) 		3 / 3 THR A  32
GLU A 206
HIS A  27
 None
 0.91A 1xwfD-2v0oA:
undetectable		 1xwfD-2v0oA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 2v0o FCH DOMAIN ONLY
PROTEIN 2
(Homo
sapiens) 		5 / 12 ILE A 227
LEU A  97
GLU A  46
LEU A  94
ARG A  42
 None
 1.22A 2bxfA-2v0oA:
3.0		 2bxfA-2v0oA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 2v0o FCH DOMAIN ONLY
PROTEIN 2
(Homo
sapiens) 		5 / 12 ILE A 227
LEU A  97
GLU A  46
LEU A  94
ARG A  42
 None
 1.22A 2bxfB-2v0oA:
3.5		 2bxfB-2v0oA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2v0o FCH DOMAIN ONLY
PROTEIN 2
(Homo
sapiens) 		4 / 5 ILE A 231
TYR A  49
MET A  53
THR A  54
 None
 1.30A 3abkN-2v0oA:
2.9
3abkW-2v0oA:
undetectable		 3abkN-2v0oA:
19.75
3abkW-2v0oA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 2v0o FCH DOMAIN ONLY
PROTEIN 2
(Homo
sapiens) 		4 / 5 HIS A 209
HIS A 112
GLN A 108
TYR A 104
 None
 1.36A 4gboB-2v0oA:
undetectable		 4gboB-2v0oA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_B_CUB301_0
(AA10A)		 2v0o FCH DOMAIN ONLY
PROTEIN 2
(Homo
sapiens) 		4 / 4 HIS A 209
HIS A 112
GLN A 108
TYR A 104
 None
 1.39A 5uizB-2v0oA:
undetectable		 5uizB-2v0oA:
20.21