SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 2v15 DNA PROTECTION
DURING STARVATION
PROTEIN
(Streptococcus
suis) 		4 / 7 ALA A 151
SER A 154
ILE A 155
ILE A  69
 None
 0.71A 1yc5A-2v15A:
undetectable		 1yc5A-2v15A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 2v15 DNA PROTECTION
DURING STARVATION
PROTEIN
(Streptococcus
suis) 		4 / 8 SER A  25
ASP A 141
SER A 136
GLN A  31
 None
 1.01A 2cmlC-2v15A:
undetectable		 2cmlC-2v15A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 2v15 DNA PROTECTION
DURING STARVATION
PROTEIN
(Streptococcus
suis) 		4 / 7 SER A  98
TYR A 124
VAL A 121
ASP A  35
 None
 0.96A 3bu1A-2v15A:
undetectable		 3bu1A-2v15A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2v15 DNA PROTECTION
DURING STARVATION
PROTEIN
(Streptococcus
suis) 		5 / 12 TYR A 124
ASP A  35
GLN A 130
ILE A 155
ILE A  69
 None
 1.25A 4drhD-2v15A:
undetectable		 4drhD-2v15A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 2v15 DNA PROTECTION
DURING STARVATION
PROTEIN
(Streptococcus
suis) 		5 / 12 LEU A  29
ASN A  30
GLY A  85
LEU A  22
PHE A  88
 None
 1.36A 4p6xA-2v15A:
undetectable		 4p6xA-2v15A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 2v15 DNA PROTECTION
DURING STARVATION
PROTEIN
(Streptococcus
suis) 		5 / 12 LEU A  29
ASN A  30
GLY A  85
LEU A  22
PHE A  88
 None
 1.32A 4p6xE-2v15A:
undetectable		 4p6xE-2v15A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2v15 DNA PROTECTION
DURING STARVATION
PROTEIN
(Streptococcus
suis) 		5 / 12 TYR A  65
LEU A  36
ALA A  39
LEU A 100
ILE A 155
 None
 1.17A 5ljcA-2v15A:
undetectable		 5ljcA-2v15A:
20.83