SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2v1n PROTEIN KIN HOMOLOG
(Homo
sapiens) 		4 / 6 LEU A  66
TRP A  63
LEU A  73
PHE A  23
 None
 1.44A 1ru9H-2v1nA:
undetectable
1ru9L-2v1nA:
undetectable		 1ru9H-2v1nA:
16.13
1ru9L-2v1nA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2v1n PROTEIN KIN HOMOLOG
(Homo
sapiens) 		4 / 6 LEU A  66
TRP A  63
LEU A  73
PHE A  23
 None
 1.45A 1rukH-2v1nA:
undetectable
1rukL-2v1nA:
undetectable		 1rukH-2v1nA:
16.13
1rukL-2v1nA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 2v1n PROTEIN KIN HOMOLOG
(Homo
sapiens) 		3 / 3 ARG A 101
ARG A 102
PRO A  97
 None
 0.97A 2wljA-2v1nA:
undetectable		 2wljA-2v1nA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2v1n PROTEIN KIN HOMOLOG
(Homo
sapiens) 		4 / 8 TRP A  72
LEU A  28
LEU A  31
ASN A  42
 None
 0.93A 3u5kD-2v1nA:
undetectable		 3u5kD-2v1nA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2v1n PROTEIN KIN HOMOLOG
(Homo
sapiens) 		3 / 3 PHE A  19
ASP A  17
LEU A  78
 None
 0.77A 5uhbC-2v1nA:
undetectable		 5uhbC-2v1nA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2v1n PROTEIN KIN HOMOLOG
(Homo
sapiens) 		3 / 3 PHE A  19
ASP A  17
LEU A  78
 None
 0.78A 5uhcC-2v1nA:
undetectable		 5uhcC-2v1nA:
7.96