SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 2v33 E1 ENVELOPE
GLYCOPROTEIN
(Semliki
Forest
virus) 		5 / 12 ALA A 337
LEU A 339
LEU A 316
SER A 368
THR A 358
 None
None
None
NO3  A1383 (-2.7A)
None
 1.12A 4ky8B-2v33A:
undetectable		 4ky8B-2v33A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 2v33 E1 ENVELOPE
GLYCOPROTEIN
(Semliki
Forest
virus) 		5 / 12 ALA A 337
LEU A 339
LEU A 316
SER A 368
THR A 358
 None
None
None
NO3  A1383 (-2.7A)
None
 1.11A 4ky8D-2v33A:
undetectable		 4ky8D-2v33A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 2v33 E1 ENVELOPE
GLYCOPROTEIN
(Semliki
Forest
virus) 		5 / 12 ALA A 337
LEU A 339
LEU A 316
SER A 368
THR A 358
 None
None
None
NO3  A1383 (-2.7A)
None
 1.11A 4ky8E-2v33A:
undetectable		 4ky8E-2v33A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_C_MTXC604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2v33 E1 ENVELOPE
GLYCOPROTEIN
(Semliki
Forest
virus) 		5 / 12 ALA A 337
LEU A 339
LEU A 316
SER A 368
THR A 358
 None
None
None
NO3  A1383 (-2.7A)
None
 0.95A 4q0dC-2v33A:
undetectable		 4q0dC-2v33A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_D_MTXD604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2v33 E1 ENVELOPE
GLYCOPROTEIN
(Semliki
Forest
virus) 		5 / 12 ALA A 337
LEU A 339
LEU A 316
SER A 368
THR A 358
 None
None
None
NO3  A1383 (-2.7A)
None
 0.95A 4q0dD-2v33A:
undetectable		 4q0dD-2v33A:
11.65